A Study to Evaluate the Efficacy and Safety of PRM-151 in Patients With Idiopathic Pulmonary Fibrosis

  • Respiratory Disorder
  • Idiopathic Pulmonary Fibrosis (IPF)
Please note that the recruitment status of the study at your site may differ from the overall study status because some study sites may recruit earlier than others.
Study Status:

Terminated

This study runs in
Cities
  • 2
  • Aarhus
  • Adana
  • Akershus
  • Amsterdam
  • Ankara
  • Antalya
  • Ashkelon
  • Athens
  • Atlanta
  • Auckland
  • Aurora
  • Bad Berka
  • Badalona
  • Barcelona
  • Be'er Sheva
  • Be'er Ya'akov
  • bei-jing-shi
  • Beijing
  • Bergen
  • Berlin
  • Bern
  • Birmingham
  • Bobigny
  • Boston
  • Braga
  • Brandon
  • Brest
  • Brno-Bohunice
  • Bron
  • Bruxelles
  • Bucheon
  • Bucheon-si
  • Budapest
  • Buenos Aires
  • Bursa
  • Bydgoszcz
  • Cairns North
  • Camperdown
  • Cape Town
  • Catania
  • celebration
  • Cesi
  • Chaidari
  • chang-sha-shi
  • Charleston
  • Charlotte
  • Cheng Du Shi
  • Chesterfield
  • Chiba
  • Chihuahua
  • Christchurch
  • Chuo City
  • Cincinnati
  • Ciudad de México
  • Clamart
  • Clayton
  • Cleveland
  • Columbia
  • Coslada
  • Cypress
  • Córdoba
  • dalin
  • Dallas
  • Daytona Beach
  • Debrecen
  • Denver
  • Dijon
  • Dnipro
  • Durham
  • Edinburgh
  • Edmonton
  • Essen
  • Evanston
  • exochi
  • Falls Church
  • Faro
  • Firenze
  • Florida
  • Foggia
  • Forlì
  • Fort Lauderdale
  • Frankfurt am Main
  • Fukuoka
  • Gainesville
  • Galdakao
  • Galveston
  • Garbagnate Milanese
  • Gaziantep
  • Gießen
  • Granada
  • Greensboro
  • guang-zhou-shi
  • Guimaraes
  • Haifa
  • Hamilton
  • hang-zhou-shi
  • Hannover
  • Heidelberg
  • Hellerup
  • highgate-hill
  • Himeji
  • Hlavní město Praha
  • Hohhot
  • Holon
  • Homburg
  • Hong Kong Island
  • Immenhausen
  • Incheon
  • Indianapolis
  • Iowa City
  • Iraklio
  • İstanbul
  • İzmir
  • Jacksonville
  • Jerusalem
  • Ji Nan Shi
  • kamogawa
  • Kansas City
  • Kaohsiung City
  • Kawasaki
  • Kayseri
  • Kefar Sava
  • Kelowna
  • Klagenfurt am Wörthersee
  • Kobe
  • Kocaeli
  • Kumamoto
  • Kurashiki
  • Kyiv
  • L'Hospitalet de Llobregat
  • La Laguna
  • La Tronche
  • Leipzig
  • Leuven
  • Lille
  • Lisboa
  • London
  • Longview
  • Louisville
  • loxahatchee-groves
  • luik
  • Madison
  • Madrid
  • Mainz
  • Majadahonda
  • Manchester
  • Mar del Plata
  • Marburg
  • Marietta
  • Marousi
  • Marseille
  • McKinney
  • Melbourne
  • Mendoza
  • Mersin
  • Messina
  • Miami Lakes
  • Milano
  • Minas Gerais
  • Minneapolis
  • Modena
  • Montpellier
  • Montréal
  • Monza
  • Morelia
  • Murdoch
  • Málaga
  • Münnerstadt
  • Nagasaki
  • nan-jing-shi
  • Nanchang
  • Napoli
  • Nashville
  • Neochoropoulo
  • neuchatel
  • New Haven
  • New Taipei City
  • New Territories
  • New York
  • Nice
  • Nieuwegein
  • ning-bo-shi
  • North Charleston
  • Ocala
  • Odense
  • olomouc-9
  • Omaha
  • Orange
  • Orlando
  • Oslo
  • ostuni
  • Oviedo
  • Owen Sound
  • Padova
  • Palermo
  • Palo Alto
  • Pamplona
  • Paris
  • Pavia
  • Pessac
  • Petah Tikva
  • Philadelphia
  • Phoenix
  • Pittsburgh
  • plze_-region
  • Portland
  • Porto
  • Pozuelo de Alarcón
  • Ramat Gan
  • Rehovot
  • Reims
  • Rennes
  • Richmond
  • Rio
  • Rio Grande do Sul
  • Rochester
  • Roma
  • Rotterdam
  • Sabadell
  • Sacramento
  • saginaw
  • Sakai
  • Salamanca
  • Salt Lake City
  • Salzburg
  • San Antonio
  • San Diego
  • San Francisco
  • San Miguel de Tucumán
  • san-juan-capistrano
  • san-nicolas-de-los-garza
  • Santa Barbara
  • Santander
  • Santiago de Compostela
  • Sarasota
  • Sassari
  • Seongnam-si
  • Seoul
  • seto
  • Sevilla
  • shang-hai-shi
  • shen-yang-shi
  • Sherwood Park
  • Shijiazhuang
  • Shimotsuke
  • Shinjuku City
  • Siena
  • Singapore
  • Skåne län
  • Solingen
  • Spartanburg
  • St. John's
  • St. Louis
  • Summit
  • Szombathely
  • Taichung City
  • Tainan City
  • Taipei City
  • Tampa
  • Tatabánya
  • Tauranga
  • Tel Aviv-Yafo
  • tenri
  • tian-jin-shi
  • Tokai
  • Tokushima
  • Toledo
  • Torino
  • Torrette
  • Tours
  • Treviso
  • Trieste
  • Trois-Rivières
  • Turku
  • Törökbálint
  • València
  • Vancouver
  • Vila Nova de Gaia
  • Vitoria-Gasteiz
  • Washington
  • Wilmington
  • Windsor
  • Winter Park
  • Woodville South
  • Woolloongabba
  • wu-han-shi
  • Wuxi
  • xi-an-shi
  • Yokohama
  • Yvoir
  • zheng-zhou-shi
  • Zhengzhou Shi
  • zlin-1
  • Łódź
  • 横浜市
Trial Identifier:

NCT04552899 2020-000791-38 WA42293

  • "Asst Rhodense - Unità operativa di pneumologia Ospedale ""Guido Salvini"" "

    95 Viale Carlo Forlanini20024Garbagnate MilaneseItaly
  • "General hospital of Chest Diseases ""Sotiria"", 7th Pulmonary Clinic "

    152 Mesogion115 27AthensGreece
  • 1st Affiliated Hospital of Zhejiang University; Clinical Trial Pharmacy

    181 文三路310005hang-zhou-shiChina
  • A.O. Univ. Senese Policlinico S. Maria alle Scotte; Dip. Medicina clinica e Scienze Immunologiche

    48 Via G. Mazzini53100SienaItaly
  • A.O.U. Policlinico di Modena

    71 Via del Pozzo41125ModenaItaly
  • A.O.U. S. Luigi Gonzaga; Interstiziopatie Malattie Rare Polmone

    10043MessinaItaly
  • A.O.U. Sassari; Dip. Medicina Clinica e Sperimentale

    10 Viale S. Pietro07100SassariItaly
  • Aarhus Universitetshospital Skejby

    99 Palle Juul-Jensens Blvd.8200AarhusDenmark
  • Advanced Pulmonary & Sleep Research Institute of Florida

    32117Daytona BeachUnited States
  • Advanced Pulmonary Research Institute

    33470loxahatchee-grovesUnited States
  • Akdeniz University Faculty of Medicine Department of Pulmonology

    07059AntalyaTürkiye
  • Akershus universitetssykehus

    1478AkershusNorway
  • American Health Research Inc.

    28277CharlotteUnited States
  • Ankara Universitesi Tip Fakultesi Hastaneleri - Cebeci Hastanesi

    9 Talatpaşa Blv06050AnkaraTürkiye
  • AORN Ospedali dei Colli Ospedale Monaldi; UOC Pneumologia ad indirizzo Oncologico

    80131NapoliItaly
  • AOUC Azienda Ospedaliero-Universitaria Careggi; Neurologia 2

    3 Largo Giovanni Alessandro Brambilla50134FirenzeItaly
  • Asan Medical Center

    05505SeoulSouth Korea
  • Asst Santi Paolo E Carlo

    18 Via Pietro Boifava20142MilanoItaly
  • Athens Medical Center

    5-7 Distomou151 25MarousiGreece
  • Attikon University General Hospital

    1 Rimini124 62ChaidariGreece
  • Auckland City Hospital

    2 Park Rd1023AucklandNew Zealand
  • Audie L. Murphy VA Hospital, STVHCS

    7400 Merton Minter78229San AntonioUnited States
  • Austin Hospital; Cancer Clinical Trials Centre

    145 Studley Rd3084HeidelbergAustralia
  • Az. Osp. Univ. P. Giaccone; UOC di Pneumologia

    90127PalermoItaly
  • Azienda Ospedale Università Di Padova; Clinica Pneumologica

    2 Via Nicolò Giustiniani35128PadovaItaly
  • Azienda Ospedaliera Dei Colli

    80131NapoliItaly
  • Azienda Ospedaliera Papa Giovanni XXIII

    24060CesiItaly
  • Azienda Ospedaliera Universitaria Citta della Salute e della Scienza di Torino; Ospedale Molinette

    88 Corso Bramante10126TorinoItaly
  • Azienda Ospedaliera Universitaria Federico II

    5 Via Sergio Pansini80131NapoliItaly
  • Azienda Ospedaliero - Universitaria Policlinico - Vittorio Emanuele

    628 Via Plebiscito95122CataniaItaly
  • Azienda Ospedaliero Universitaria Ospedali Riuniti

    71 Via Conca60126TorretteItaly
  • Azienda Sanitaria Universitaria Integrata di Trieste

    7 Via Giovanni Sai34128TriesteItaly
  • Banner University Medical Center Phoenix; Main Pharmacy

    1111 E McDowell Rd85006PhoenixUnited States
  • Barzilai Medical Center; Neurology Department

    2 Ha-Histadrut St7830604AshkelonIsrael
  • Beijing Friendship Hospital Affiliated of Capital University of Medical Science

    100050BeijingChina
  • Ben-Gurion University of the Negev - Soroka University Medical Center - Pulmonology Institute

    8410101Be'er ShevaIsrael
  • Bnai Zion Medical Center; Internal Medicine

    47 Sderot Eliyahu Golomb3339419HaifaIsrael
  • Brigham & Women'S Hospital

    75 Francis St02115BostonUnited States
  • Buddhist Tzu Chi Dalin General Hospital; Rheumatology

    622dalinTaiwan
  • C. H. U. Sart-Tilman; Laboratory

    1 Avenue de l'Hôpital4000luikBelgium
  • C.I.C. Mauricie

    G8T 7A1Trois-RivièresCanada
  • Cairns Base Hospital; Cancer Care Centre

    165 Esplanade4870Cairns NorthAustralia
  • Cardiopulmonary Research Science and Technology Institute

    75230DallasUnited States
  • Carmel Medical Center; Obstetrics and Gynecology

    34362HaifaIsrael
  • Center Hospital of the National Center for Global Health and Medicine

    162-8655Shinjuku CityJapan
  • Central Florida Pulmonary Group, PA

    1115 E Ridgewood St32803OrlandoUnited States
  • Centre Hospitalier de l'Universite de Montreal - Notre - Dame Hos pital

    1051 Rue SanguinetH2X 3E4MontréalCanada
  • Centre Hospitalier Regional Universitaire de Brest - Hopital de la Cavale Blanche

    29609 Bd Tanguy Prigent29200BrestFrance
  • Centre Hospitalier Regional Universitaire de Lille

    2 Av. Oscar Lambret59000LilleFrance
  • Centre Hospitalier Universitaire de Reims; l'Hopital Maison Blanche

    45 Rue Cognacq-Jay51100ReimsFrance
  • Centro de estudios respiratorios

    B7600CLKMar del PlataArgentina
  • Centro Hospitalar Algarve

    8000-386FaroPortugal
  • Centro Hospitalar do Porto - Hospital de Santo António

    4099-001PortoPortugal
  • Centro Hospitalar Universitario Lisboa Norte - Hospital Pulido Valente

    117 Alameda das Linhas de Torres1769-001LisboaPortugal
  • Centro Medico de Enfermedades Respiratorias (CEMER)

    B1602DQDFloridaArgentina
  • Centro Respiratorio de México

    57 Tepepan14050Ciudad de MéxicoMexico
  • Centrum Medycyny Oddechowej Mroz sp. j.

    15-044Poland
  • Chiba University Hospital

    260-8677ChibaJapan
  • China Medical University (CMU) First Affiliated Hospital

    92号 北二马路110052shen-yang-shiChina
  • China Medical University Hospital

    40447Taichung CityTaiwan
  • China-Japan Friendship Hospital

    2 Ying Hua Yuan Dong Jie100013bei-jing-shiChina
  • CHU de Grenoble - Hôpital André Michallon; Pole Pharmacie

    38700La TroncheFrance
  • CHU de Montpellier Hopital Arnaud de Villeneuve; de Génétique

    191 Av. du Doyen Gaston Giraud34295MontpellierFrance
  • CHU de Rennes - Hopital de Pontchaillo

    35033RennesFrance
  • CHU Dijon Bourgogne Hôpital François Mitterand

    2B Bd Maréchal de Lattre de Tassigny21000DijonFrance
  • CHU Nice - Hôpital Pasteur 2

    06000NiceFrance
  • CHU Tours - Hôpital Bretonneau; Pharmacie

    2 Bd Tonnellé37000ToursFrance
  • CHU UCL Namur / site Godinne

    1 Rue Dr Gaston Therasse5530YvoirBelgium
  • CHVNG/E_Unidade 1; Servico de Pneumologia

    S/N R. Conceição Fernandes4434-502Vila Nova de GaiaPortugal
  • CICC Morelia

    58030MoreliaMexico
  • Clínica Universidad de Navarra ? Madrid

    1 C. del Marquesado de Sta. Marta28027MadridSpain
  • Clinical Site Partners Orlando

    32789Winter ParkUnited States
  • Cliniques Universitaires Saint-Luc; Pharmacy

    10 Av. Hippocrate1200BruxellesBelgium
  • CMU-Beijing Chao-Yang Hospital-Beijing Institute of Respiratory Medicine

    100020BeijingChina
  • Complexo Hospitalario Universitario de Santiago (CHUS) - Hospital Clinico Universitario

    s/n Rúa da Choupana15706Santiago de CompostelaSpain
  • Covenant Medical Center - Cooper

    700 Cooper Ave48602saginawUnited States
  • Cukurova Universitesi Tip Fakultesi Balcali Hastanesi; Balcali

    01790AdanaTürkiye
  • DCOL Center for Clinical Research

    75605-2410LongviewUnited States
  • Debreceni Egyetem

    4032DebrecenHungary
  • Dokuz Eylul University Faculty of Medicine; Chest Diseases

    35340İzmirTürkiye
  • Dr. Syed Anees Medicine Profession Corporation

    2462 Howard AveN8X 3V6WindsorCanada
  • Duke University Medical Center

    27710DurhamUnited States
  • Eastern Health - General Hospital

    300 PPDA1B 3V6St. John'sCanada
  • Edinburgh Royal Infirmary; Respiratory Department

    51 Old Dalkeith RdEH16 4SAEdinburghUnited Kingdom
  • Edith Wolfson Medical Center

    62 Ha-Lokhamim St5822012HolonIsrael
  • Ege Universitesi Tip Fakultesi Hastanesi

    No:9 Üniversite Cd.35100İzmirTürkiye
  • Emory University

    201 Dowman Dr30322AtlantaUnited States
  • Erasmus Medisch Centrum

    3000 CARotterdamNetherlands
  • Erciyes Üniversitesi T?p Fakültesi

    38039KayseriTürkiye
  • European Hospital Georges Pompidou (HEGP)

    20 Rue Leblanc75015ParisFrance
  • Evang. Lungenklinik Berlin Klinik für Pneumologie

    27 Lindenberger Weg13125BerlinGermany
  • Evangelismos Hospital; Department of Critical Care and Pulmonary Services

    45-47 Ipsilantou106 76AthensGreece
  • Fakultní Nemocnice Brno

    20 Jihlavská625 00Brno-BohuniceCzechia
  • Fakultni nemocnice Olomouc

    248/7 Zdravotníků779 00olomouc-9Czechia
  • Fakultni Nemocnice Plzen - Klinika Pneumologie a Ftizeologie

    301 00plze_-regionCzechia
  • Far Eastern Memorial Hospital; Department of Clinical Pathology

    21號 Section 2, Nanya S Rd220New Taipei CityTaiwan
  • Fiona Stanley Hospital

    11 Robin Warren Dr6150MurdochAustralia
  • Florida Lung, Asthma and Sleep Specialists (FLASS) - Celebration

    34747celebrationUnited States
  • Fondazione IRCCS Policlinico San Matteo Divisione di EmatologiaDipartimento di Onco-Ematologia

    17 Piazzale Camillo Golgi27100PaviaItaly
  • Fondazione Policlinico Universitario A Gemelli; Servizio di Farmacia

    31 Via Giuseppe Moscati00168RomaItaly
  • Fukuoka University Hospital

    814-0180FukuokaJapan
  • Fundacion Respirar (Centro Medico Dra. De Salvo)

    1548 Av. CabildoC1426ABPBuenos AiresArgentina
  • Fundacion Scherbovsky

    2760 José Federico MorenoM5500MendozaArgentina
  • Gacheon University Gil Medical Center

    21565IncheonSouth Korea
  • Gaziantep Universitesi - Sahinbey Arastirma ve Uygulama Hastanesi

    27310GaziantepTürkiye
  • General Hospital of Thessaloniki G. Papanikolaou

    570 10exochiGreece
  • Gentofte Hospital

    1 Gentofte Hospitalsvej2900HellerupDenmark
  • Georgetown University Medical Center

    20057WashingtonUnited States
  • Hadassah Medical Center

    9112001JerusalemIsrael
  • Hebei Medical University - The Second Hospital

    050004ShijiazhuangChina
  • Helse Bergen HF Haukeland universitetssykehus

    22 Haukelandsveien5009BergenNorway
  • Henan University of Traditional Chinese Medicine (HUTCM) The First Affiliated Hospital

    450000Zhengzhou ShiChina
  • Hopital Avicenne

    125 Rue de Stalingrad93000BobignyFrance
  • Hopital Bichat Claude Bernard; CIC

    46 Rue Henri Huchard75018ParisFrance
  • Hopital Haut Leveque

    33600PessacFrance
  • Hopital Louis Pradel

    69500BronFrance
  • Hopital Neuchatelois Pourtales (Hopitaux Cadolles Pourtales)

    45 Rue de la Maladière2000neuchatelSwitzerland
  • Horizon Clinical Research Group

    77429CypressUnited States
  • Hosp. Clinico San Carlos

    S/N Calle del Prof Martín Lagos28040MadridSpain
  • Hospital Arnau de Vilanova (Valencia)

    12 Carrer de Sant Clement46015ValènciaSpain
  • Hospital Britanico de Buenos Aires

    74 PerdrielC1280Buenos AiresArgentina
  • Hospital Clinic de Barcelona

    170 C. de Villarroel08036BarcelonaSpain
  • Hospital Clinico Universitario de Salamanca

    182 P.º de San Vicente37007SalamancaSpain
  • Hospital Clinico Universitario de Valencia

    17 Av. de Blasco Ibáñez46010ValènciaSpain
  • Hospital Clinico Universitario Virgen de la Victoria

    S/N Campus de Teatinos29010MálagaSpain
  • Hospital d Instructions des Armees Percy

    2 Rue Lieutenant Raoul Batany92140ClamartFrance
  • Hospital das Clinicas - UFMG

    110 Av. Prof. Alfredo Balena30130-100Minas GeraisBrazil
  • Hospital de Braga; Centro Clínico Académico (Piso 1, Ala E)

    4710-243BragaPortugal
  • Hospital de la Santa Creu i Sant Pau; Servicio de Neumologia

    89 C/ de Sant Quintí08041BarcelonaSpain
  • Hospital de Santa Luzia

    4904-858PortoPortugal
  • Hospital de Sao Joao; Centro de Investigacao

    4200-319PortoPortugal
  • Hospital Galdakao-Usansolo

    48960GaldakaoSpain
  • Hospital Germans Trias i Pujol

    s/n Carretera de Canyet08916BadalonaSpain
  • Hospital is University General Hospital of Larissa

    413 34Greece
  • Hospital Ramón y Cajal;Servicio de Neumología

    Km. 9 M-60728034MadridSpain
  • Hospital Senhora da Oliveira ? Guimarães, E.P.E

    4835-044GuimaraesPortugal
  • Hospital Txagorritxu

    01009Vitoria-GasteizSpain
  • Hospital Universitari i Politecnic La Fe de Valencia

    106 Avinguda de Fernando Abril Martorell46026ValènciaSpain
  • Hospital Universitario 12 de Octubre

    s/n Av. de Córdoba28041MadridSpain
  • Hospital Universitario Central de Asturias

    s/n Av. Roma33011OviedoSpain
  • Hospital Universitario de Bellvitge

    s/n Carrer de la Feixa Llarga08907L'Hospitalet de LlobregatSpain
  • Hospital Universitario de Canarias

    38320La LagunaSpain
  • Hospital Universitario de La Princesa

    62 Calle de Diego de León28006MadridSpain
  • Hospital Universitario del Henares

    0 Av. de Marie Curie28822CosladaSpain
  • Hospital Universitario Fundacion Jimenez Diaz.

    2 Av. de los Reyes Católicos28040MadridSpain
  • Hospital Universitario La Paz

    261 P.º de la Castellana28046MadridSpain
  • Hospital Universitario Marques de Valdecilla

    s/n Av. de Valdecilla39008SantanderSpain
  • Hospital Universitario Puerta de Hierro - Majadahonda

    1 C. Joaquín Rodrigo28222MajadahondaSpain
  • Hospital Universitario Quironsalud Madrid

    1 C. Diego de Velázquez28223Pozuelo de AlarcónSpain
  • Hospital Universitario Virgen del Rocio

    S/n Av. Manuel Siurot41013SevillaSpain
  • Hospital Virgen de las Nieves; Servicio de Neumologia

    2 Av. de las Fuerzas Armadas18014GranadaSpain
  • Huadong Hospital Affiliated to Fudan University

    221 Yan An Xi Lu200031shang-hai-shiChina
  • IFS - Interdisziplinäres Facharztzentrum; Institut für klinische Forschung Pneumologie

    26 Senckenberganlage60325Frankfurt am MainGermany
  • IKF Pneumologie Mainz Helix Medical Excellence Center Mainz

    55128MainzGermany
  • Indiana Univ School of Med

    1160 W Michigan St46202IndianapolisUnited States
  • INER- Instituto Nacional de Enfermedades Respiratorias"Ismae

    4502 Calz. de Tlalpan14080Ciudad de MéxicoMexico
  • Inner Mongolia Autonomous Region People's Hospital

    010011HohhotChina
  • Inova Fairfax Hospital/IHVI; Cardiology

    3300 Gallows Rd22042Falls ChurchUnited States
  • INSARES

    M5500CCGMendozaArgentina
  • Inselspital Bern Universitätsklinik für Pneumologie

    20 Freiburgstrasse3010BernSwitzerland
  • Inst. of Healthcare Assessment, Inc.

    5555 Reservoir Dr92120San DiegoUnited States
  • Instituto de Medicina Respiratoria, IMeR; Clinic/Outpatient Facility

    X5003DCECórdobaArgentina
  • Integral ? Clinical Trial Solutions

    33327Fort LauderdaleUnited States
  • Investigaciones en Patologias Respiratorias

    T4000IARSan Miguel de TucumánArgentina
  • Ismett Istituto Mediterraneo Trapianti E Terapie Alta Specializzazione;Pneumologia

    5 Via Ernesto Tricomi90127PalermoItaly
  • Istanbul Universitesi Onkoloji Enstitüsü Hastanesi

    No:118 Turgut Özal Millet Cd34093İstanbulTürkiye
  • Jefferson University Physicians (JUP) - Jefferson Pulmonary

    833 Chestnut St19107PhiladelphiaUnited States
  • Jichi Medical University Hospital

    329-0431ShimotsukeJapan
  • Kameda Medical Center

    296-0041kamogawaJapan
  • Kanagawa Cardiovascular and Respiratory Center

    236-0051YokohamaJapan
  • Kaohsiung Medical University Hospital; Chung-Ho Memorial Hospital

    100號 Ziyou 1st Rd80756Kaohsiung CityTaiwan
  • Kaplan Medical Center

    1 Derech Pasternak7610001RehovotIsrael
  • Kelowna Respiratory and Allergy Clinic

    1835 Gordon DrV1Y 3H5KelownaCanada
  • Klinikum Klagenfurt am Wörthersee; 2. Medizinische Abteilung

    11 Feschnigstraße9020Klagenfurt am WörtherseeAustria
  • Kobe City Medical Center General Hospital

    650-0047KobeJapan
  • Koc Universitesi (KU) Tip Fakultesi (Koc University School of Medicine)

    34450İstanbulTürkiye
  • Kocaeli Universitesi Tip Fakultesi

    41001KocaeliTürkiye
  • Korea University Guro Hospital

    08308SeoulSouth Korea
  • Krajská nemocnice T. Bati, a. s.

    762 75zlin-1Czechia
  • Krankenhaus Bethanien gGmbH

    169 Aufderhöher Str.42699SolingenGermany
  • Kurashiki Central Hospital

    710-0052KurashikiJapan
  • Landeskrankenhaus Salzburg; Gynäkologie Und Onkologie

    48 Müllner Hauptstraße5020SalzburgAustria
  • Lenox Hill Hospital

    100 E 77th St10075New YorkUnited States
  • Lovelace Scientific Resources, Inc.

    3001 W Pima St85009PhoenixUnited States
  • Lowcountry Lung and Critical Care

    9150 Medcom St29406North CharlestonUnited States
  • Lung Research Queensland

    4101highgate-hillAustralia
  • Lungenfachklinik Immenhausen

    3 Robert-Koch-Straße34376ImmenhausenGermany
  • Lungenklinik Münnerstadt, Thoraxzentrum Bezirk Unterfranken

    1 Michelsberg97702MünnerstadtGermany
  • Malcom Randall VA Medical Center

    1601 SW Archer Rd32608GainesvilleUnited States
  • Manchester University NHS Foundation Trust - Wythenshawe Hospital

    100 Southmoor RdM23 9QZManchesterUnited Kingdom
  • Markusovszky Egyetemi Oktatokorhaz ; SZEMESZET

    5 Markusovszky Lajos u.9700SzombathelyHungary
  • Marmara Universitesi Hastanesi Marmara University Hospital

    34854İstanbulTürkiye
  • Massachusetts General Hospital

    55 Fruit St02114BostonUnited States
  • Mayo Clinic Rochester

    1216 2nd St SW55902RochesterUnited States
  • McGill University, Montreal Chest Institute; Viral and other Infectious

    1001 Bd DécarieH4A 3J1MontréalCanada
  • Medical University of South Carolina Hospital

    268 Calhoun St29425CharlestonUnited States
  • Medizinische Hochschule Hannover; Zentrum Innere Medizin - Klinik fur Pneumologie

    1 Carl-Neuberg-Straße30625HannoverGermany
  • Meir Medical Center

    59 Tchernichovsky St4428164Kefar SavaIsrael
  • Mercy St. Vincent Medical Center

    2213 Cherry St43608ToledoUnited States
  • Meris Clinical Research

    310 Oakfield Dr33511BrandonUnited States
  • Mersin Üniversitesi Tip Fakültesi

    33079MersinTürkiye
  • Metroplex Pulmonology & Sleep Center

    75069McKinneyUnited States
  • Monash Medical Centre; Medicine

    246 Clayton Rd3168ClaytonAustralia
  • Municipal Non-Profit Enterprise City Clinical Hospital #16 of Dnipro City Council

    49000DniproUkraine
  • Nagasaki University Hospital

    852-8501NagasakiJapan
  • Nagoya University Hospital

    466-8560横浜市Japan
  • Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School

    321 Zhong Shan Lu210008nan-jing-shiChina
  • Nasz Lekarz Osrodek Badan Klinicznych

    6 Tytusa Chałubińskiego85-794BydgoszczPoland
  • National Academy of Medical Science of Ukraine (NAMS); NRCRM

    02000KyivUkraine
  • National Cheng Kung University Hospital

    138號 Shengli Rd704Tainan CityTaiwan
  • National Hospital Organization Himeji Medical Center

    670-0012HimejiJapan
  • National Hospital Organization Ibarakihigashi National Hospital; Center for Clinical Research

    319-1113TokaiJapan
  • National Hospital Organization Kinki-Chuo Chest Medical Center

    591-8025SakaiJapan
  • National Hospital Organization Kyushu Medical Center

    810-0065FukuokaJapan
  • National Jewish Health Medical Center

    80045-2541DenverUnited States
  • National Taiwan University Hospital

    7號 Zhongshan S Rd100Taipei CityTaiwan
  • Nemocnice Na Bulovce

    2 Budínova180 00Hlavní město PrahaCzechia
  • Ningbo First Hospital

    59 Liu Ting Jie315016ning-bo-shiChina
  • Nippon Medical School Musashi Kosugi Hospital

    211-8533KawasakiJapan
  • North Manchester General Hospital

    M8 5RBManchesterUnited Kingdom
  • NorthShore University HealthSystem

    1007 Church St60201EvanstonUnited States
  • NZ Respiratory & Sleep Institute

    93-95 Ascot Ave1051AucklandNew Zealand
  • Odense Universitetshospital

    4 J. B. Winsløws Vej5000OdenseDenmark
  • Oregon Health and Science University

    3181 SW Sam Jackson Park Rd97239PortlandUnited States
  • Oslo University Hospital HF, Rikshospitalet

    0424OsloNorway
  • Ospedale di Ostuni - Pneumologia

    72017ostuniItaly
  • Ospedale Morgagni Pierantoni; Patologia clinica

    34 Via Carlo Forlanini47121ForlìItaly
  • Ospedale San Gerardo

    33 Via G. B. Pergolesi20900MonzaItaly
  • Ospedale San Giuseppe; U.O. di Pneumologia

    12 Via San Vittore20123MilanoItaly
  • Paloma Medical Group

    30230 Rancho Viejo Rd92675san-juan-capistranoUnited States
  • Parc Taulí Sabadell Hospital Universitari

    1 Parc Taulí08208SabadellSpain
  • Peking Union Medical College Hospital; Pharmacy

    100006bei-jing-shiChina
  • Peking University Third Hospital

    49 Hua Yuan Bei Lu100191bei-jing-shiChina
  • Piedmont Healthcare Pulmonary and Critical Care Research

    30106MariettaUnited States
  • PMG Research of Wilmington

    1907 Tradd Ct28401WilmingtonUnited States
  • Policlinico Riuniti di Foggia - Department of Medical and Surgical Sciences - University of Foggia

    1 Viale Pinto Luigi71122FoggiaItaly
  • Policlinico Tor Vergata - U.O.C. Malattie Apparato Respiratorio

    81 Viale Oxford00133RomaItaly
  • Praxis für Pneumologie Dr. Silke Mronga & Dr. Lukas Jerrentrup

    3 Biegenstraße35037MarburgGermany
  • Prince of Wales Hospital; Dept. of Medicine & Therapeutics

    New TerritoriesHong Kong
  • Princess Alexandra Hospital

    199 Ipswich Rd4102WoolloongabbaAustralia
  • Pulmonary & Allergy Associates

    07901SummitUnited States
  • Pulmonix Research

    3511 W Market St27403GreensboroUnited States
  • Qilu Hospital of Shandong University

    250012Ji Nan ShiChina
  • Qinghai Provincial People?s Hospital

    2号 Gong He Lu8100072China
  • Rabin Medical Center

    39 Zeev Jabotinsky St4941492Petah TikvaIsrael
  • Rambam Health Care Campus

    8 HaAliya HaShniya St3109601HaifaIsrael
  • Renstar Medical Research

    21 NE 1st Ave34470OcalaUnited States
  • Royal Brompton Hospital; Respiratory Department

    SW3 6NPLondonUnited Kingdom
  • Royal Prince Alfred Hospital

    50 Missenden Rd2050CamperdownAustralia
  • Ruijin Hospital Shanghai Jiaotong University School of Medicine

    197号 瑞金二路200031shang-hai-shiChina
  • Saiseikai Kumamoto Hospital

    861-4193KumamotoJapan
  • Samsung Medical Center

    06351SeoulSouth Korea
  • San Marcus Research Clinic Inc.

    16420 NW 59th Ave33014Miami LakesUnited States
  • Santa Casa de Misericordia de Porto Alegre

    295 Rua Professor Annes Dias90020-090Rio Grande do SulBrazil
  • Sarasota Memorial Health Care System; Cancer Research Program

    1700 S Tamiami Trail34239SarasotaUnited States
  • Semmelweis University

    26 Üllői út1085BudapestHungary
  • Seoul National University Bundang Hospital

    13620Seongnam-siSouth Korea
  • Seoul National University Hospital (SNUH) - Medical Oncology Center

    03080SeoulSouth Korea
  • Servie de Pneumologie et centre de Transplantation Pulmonaire

    13354MarseilleFrance
  • Shaare Zedek Medical Center; Nrphrology Dept.

    12 Shmuel (Hans) Beyth St9103102JerusalemIsrael
  • Shamir medical center

    0070300Be'er Ya'akovIsrael
  • Shanghai Pulmonary Hospital

    507 政民路200437shang-hai-shiChina
  • Shengjing Hospital of China Medical University

    36 San Hao Jie110055shen-yang-shiChina
  • Singapore General Hospital

    169608SingaporeSingapore
  • Sint Antonius Ziekenhuis, locatie Nieuwegein

    3430 EMNieuwegeinNetherlands
  • Skånes universitetssjukhus Malmö

    47 Inga Marie Nilssons gata214 28Skåne länSweden
  • SleepMed of South Carolina

    29201-2953ColumbiaUnited States
  • Soon Chun Hyang University Hospital Bucheon

    420-767Bucheon-siSouth Korea
  • Soonchunhyang University Hospital

    04401SeoulSouth Korea
  • Southern Medical University Nanfang Hospital

    1838 Guang Zhou Da Dao Bei510515guang-zhou-shiChina
  • Spartanburg Medical Center

    101 E Wood St29303SpartanburgUnited States
  • Stanford Hospital and Clinics

    94304Palo AltoUnited States
  • Synergy Respiratory Care

    501 Bethel DrT8H 0N2Sherwood ParkCanada
  • Szent Borbala Korhaz

    77 Dózsa György út2800TatabányaHungary
  • Tan Tock Seng Hospital; Oncology

    11 Jln Tan Tock Seng308433SingaporeSingapore
  • Tangdu Hospital, The Fourth Military Medical University; Neurology Department

    710033xi-an-shiChina
  • Tauranga Hospital

    829 Cameron Rd3112TaurangaNew Zealand
  • Tel-Aviv Sourasky Medical Center; Department of Pulmonary

    6 Weizmann St64239Tel Aviv-YafoIsrael
  • Temple University Medical Center

    3223 N Broad St19140PhiladelphiaUnited States
  • Tenri Hospital

    632-0015tenriJapan
  • The 1st Affiliated Hospital of Nanchang Unversity

    330006NanchangChina
  • The Alfred Hospital

    55 Commercial Rd3004MelbourneAustralia
  • The Catholic University of Korea Bucheon St. Mary's Hospital

    14647BucheonSouth Korea
  • The Catholic University of Korea Seoul St. Mary?s Hospital

    06591SeoulSouth Korea
  • The Catholic University of Korea Yeouido St. Mary's Hospital; Hematology-Oncology

    07345SeoulSouth Korea
  • The Chaim Sheba Medical Center

    2 Derech Sheba5211401Ramat GanIsrael
  • The First Affiliated Hospital of Guangzhou Medical University

    510120guang-zhou-shiChina
  • The First Affiliated Hospital of Zhengzhou University

    1 建设东路450052zheng-zhou-shiChina
  • The First Affilicated Hospital, Sun Yat-sen University

    135号 新港西路510275guang-zhou-shiChina
  • The Lung Research Center

    222 S Woods Mill Rd63017ChesterfieldUnited States
  • The Queen Elizabeth Hospital

    28 Woodville Rd5011Woodville SouthAustralia
  • The Rhema Research Institute

    N4K 6M9Owen SoundCanada
  • The Second Xiangya Hospital of Central South University

    139 Ren Min Zhong Lu410011chang-sha-shiChina
  • The Third Xiangya Hospital Of Central South University

    138 Tong Zi Po Lu410013chang-sha-shiChina
  • The University of Hong Kong; Queen Mary Hospital

    Hong Kong IslandHong Kong
  • Thomayerova nemocnice; Lekarna - pavilon H

    813/5 Thomayerova140 00Hlavní město PrahaCzechia
  • Thoraxklinik-Heidelberg gGmbH; Apotheke der Thoraxklinik

    1 Röntgenstraße69126HeidelbergGermany
  • Tianjin Medical University General Hospital

    154 An Shan Dao300052tian-jin-shiChina
  • Tokushima University Hospital

    770-0042TokushimaJapan
  • Tokyo Medical Ando Dentaluni Hospital Faculty of Medicine; Surgical Oncology

    104-0031Chuo CityJapan
  • Tongji Hospital Tongji Medical College Huazhong University of Science and Technology

    430014wu-han-shiChina
  • Tosei General Hospital

    489-8642setoJapan
  • Tudogyogyintezet Torokbalint; Onkologiai és Jarobeteg Centrum

    70 Munkácsy Mihály u.2045TörökbálintHungary
  • Turku University Hospital

    20521TurkuFinland
  • UC Irvine Medical Center

    101 The City Dr S92868OrangeUnited States
  • UCSF Medical Center

    94143-0748San FranciscoUnited States
  • ULB Hôpital Erasme

    808 Rte de Lennik1070BruxellesBelgium
  • Uludag Universitesi - Saglik Uygulama ve Arastirrma Merkezi

    16140BursaTürkiye
  • Unidad de Investigacion CIMA SC

    31200ChihuahuaMexico
  • Unidad Médica para la Salud Integral UMSI

    440 C. Río Conchos66465san-nicolas-de-los-garzaMexico
  • Universidad de Navarra - Clinica Universitaria de Navarra (CUN)

    36 Av. de Pío XII31008PamplonaSpain
  • Università degli Studi di Napoli Federico II; Dipartimento di Scienze Oftalmologiche

    5 Via Sergio Pansini80131NapoliItaly
  • Universitätsklinikum des Saarlandes; Klinik für Augenheilkunde

    22 Gebäude66421HomburgGermany
  • Universitatsklinikum Essen; Innere Klinik

    55 Hufelandstraße45147EssenGermany
  • Universitatsklinikum Gießen und Marburg GmbH

    35GießenGermany
  • Universitatsklinikum Leipzig; Apotheke

    20 Liebigstraße04103LeipzigGermany
  • University General Hospital of Heraklion

    711 10IraklioGreece
  • University General Hospital of Patras

    265 04RioGreece
  • University Hospital of Ioannina; Pulmonology Department

    455 00NeochoropouloGreece
  • University Hospitals Cleveland Medical Center

    11100 Euclid Ave44106ClevelandUnited States
  • University of Alabama at Birmingham

    35294BirminghamUnited States
  • University of Alberta Hospital

    8440 112 St NWT6G 2B7EdmontonCanada
  • University of California Davis

    4501 X St95817SacramentoUnited States
  • University of Cape Town Lung Institute; Lung Clinical Research

    7700Cape TownSouth Africa
  • University of Cincinnati Cancer Institute

    2600 Clifton Ave45221CincinnatiUnited States
  • University of Colorado - Anschutz Medical Campus (University of Colorado Health Sciences Center)

    13001 E 17th Pl80045AuroraUnited States
  • University of Florida Division of Pulmonary, Critical Care, and Sleep Medicine

    32608-3928GainesvilleUnited States
  • University of Florida Health Pulmonology - Jacksonville

    653 8th St W32209JacksonvilleUnited States
  • University of Iowa Hospitals and Clinics; Investigational Drug Services

    200 Hawkins Dr52242Iowa CityUnited States
  • University of Kansas Medical Center

    2060 W 39th Ave66103Kansas CityUnited States
  • University of Louisville Health Sciences Center

    580 S Preston St40202LouisvilleUnited States
  • University of Minnesota Medical Center

    500 SE Harvard St55455MinneapolisUnited States
  • University of Nebraska Medical Center

    68198-0600OmahaUnited States
  • University of Otago, Christchurch

    2 Riccarton Ave8011ChristchurchNew Zealand
  • University of Padova Ca' Foncello Hospital Immunologic & Respiratory Rare Diseases Center

    13 Riviera Garibaldi31100TrevisoItaly
  • University of Pittsburgh Medical Center

    200 Meyran Ave15213PittsburghUnited States
  • University of South Florida

    4202 E Fowler Ave33620TampaUnited States
  • University of Texas Medical Branch; Cardiology Department

    301 University Blvd77555GalvestonUnited States
  • University of Texas Southwestern Medical Center; Heart and Lung Clinic

    5939 Harry Hines Blvd75390DallasUnited States
  • University Of Utah Hosp & Clin; Investigational Pharmacy

    84132Salt Lake CityUnited States
  • University of Wisconsin-Madison

    53792MadisonUnited States
  • Uniwersytecki Szpital Kliniczny Nr 1 im.N.Barlickiego Oddzial Kliniczny Pneumonologii i Alergologii

    22 dr. Stefana Kopcińskiego90-153ŁódźPoland
  • UZ Leuven

    49 Herestraat3000LeuvenBelgium
  • Vall d?Hebron Institute of Oncology (VHIO), Barcelona

    08035BarcelonaSpain
  • Vancouver General Hospital; Gordon and Leslie Diamond Health Care

    2775 Laurel StV5Z 1M9VancouverCanada
  • Vanderbilt University Medical Center

    2215 Garland Ave37232NashvilleUnited States
  • Vergelegen Medi-Clinic

    7130Cape TownSouth Africa
  • Veterans General Hospital - Taichung

    407Taichung CityTaiwan
  • Virginia Commonwealth University

    907 Floyd Ave23284RichmondUnited States
  • VU Medisch Centrum

    1117 De Boelelaan1081 HVAmsterdamNetherlands
  • Waikato Hospital; Gastro Research

    183 Pembroke St3204HamiltonNew Zealand
  • Washington University

    1 Brookings Dr63130St. LouisUnited States
  • West China Hospital, Sichuan University

    37 Guo Xue Xiang610041Cheng Du ShiChina
  • William Sansum Diabetes Center

    2219 Bath St93105Santa BarbaraUnited States
  • Wuxi People's Hospital

    214023WuxiChina
  • Xiangya Hospital Central South University

    410008chang-sha-shiChina
  • Yale New Haven Hospital

    20 York St06510New HavenUnited States
  • Yanovskyy Inst of Phth. & Pulm; Clinical-functional

    02000KyivUkraine
  • Yedikule Gogus Hastaliklari ve Gogus Cerrahisi EAH;Gogus Hastaliklari

    34020İstanbulTürkiye
  • Zentralklinik Bad Berka GmbH; Pneumologie

    99Bad BerkaGermany
    Show study locations

    The source of the below information is public registry websites such as ClinicalTrials.gov, EuClinicalTrials.eu, ISRCTN.com, etc.. It has been summarised and edited into simpler language. For more information about this clinical study see the For Expert tab on the specific ForPatients page or follow these links to https://clinicaltrials.gov and/or https://euclinicaltrials.eu and/or https://www.isrctn.com.

    The below information is taken directly from public registry websites such as ClinicalTrials.gov, EuClinicalTrials.eu, ISRCTN.com, etc., and has not been edited.

    Results Disclaimer

    Study Summary

    This phase III study will evaluate the efficacy, safety and pharmacokinetics (PK) of recombinant human pentraxin-2 (rhPTX-2; PRM-151) zinpentraxin alfa, compared with placebo in participants with idiopathic pulmonary fibrosis (IPF).

    Hoffmann-La Roche Sponsor
    Phase 3 Phase
    NCT04552899, WA42293, 2020-000791-38 Trial Identifier
    PRM-151 (Zinpentraxin Alfa), Placebo Treatments
    Idiopathic Pulmonary Fibrosis Condition
    Official Title

    A Phase III Randomized, Double-blind, Placebo Controlled Trial to Evaluate the Efficacy and Safety of PRM-151 in Patients With Idiopathic Pulmonary Fibrosis

    Eligibility Criteria

    All Gender
    ≥40 Years & ≤ 85 Years Age
    No Healthy Volunteers
    Inclusion Criteria
    • Documented diagnosis of IPF per the 2018 American Thoracic Society (ATS)/European Respiratory Society (ERS)/Japanese Respiratory Society (JRS)/Latin American Thoracic Society (ALAT) Clinical Practice Guideline
    • High-resolution computed tomography (HRCT) pattern consistent with the diagnosis of IPF, confirmed by central review of Chest HRCT and central review of any available lung biopsy (LB)
    • Minimum 6 minute walk distance (6MWD) of 150 meters with maximum use of 6 L/min at sea-level and up-to 8 L/min at altitude of supplemental oxygen while maintaining oxygen saturation of greater than or equal to (>/= )83% during the 6 minute walk test (6MWT) during screening
    • FVC >/= 45% predicted during screening as determined by the over-reader
    • Forced expiratory volume in 1 second (FEV1)/FVC ratio greater than (>) 0.70 during screening determined by the over-reader
    • Diffusing capacity for carbon monoxide (DLCO) >/= 30% and less than or equal to (</=) 90% of predicted at screening as determined by the over-reader
    • If receiving pirfenidone or nintedanib treatment for IPF, the participant must have been on treatment for at least 3 months and a stable dose for at least 4 weeks prior to screening, and during screening
    • If not currently receiving nintedanib or pirfenidone treatment (either treatment naïve or having previously taken and discontinued) must have discontinued such treatment >/= 4 weeks prior to screening and during screening
    • Anticipated life expectancy of at least 12 months at baseline
    • Participant and investigator considered all medicinal treatment options and/or possibly lung transplantation prior to considering participation in the study.
    • For women of childbearing potential (excluding participant enrolling in Japan): agreement to remain abstinent or use contraception
    • For men: agreement to remain abstinent or use a condom, and agreement to refrain from donating sperm
    • Anticipated life expectancy of at least 12 months at baseline, according to the investigator's judgment
    • For participant enrolled in the extended China enrollment phase: current resident of mainland China, Hong Kong, or Taiwan, and of Chinese ancestry
    Exclusion Criteria
    • Evidence of other known causes of Interstitial Lung Disease (ILD)
    • FVC% predicted value showing repeated increase in the 6 months period prior to screening and including screening value
    • Emphysema present on greater than or equal to (>/=) 50% of the HRCT, or the extent of emphysema is greater than the extent of fibrosis, according to central review of the HRCT
    • Receiving nintedanib in combination with pirfenidone
    • Received cytotoxic, immunosuppressive, cytokine modulating, or receptor antagonist agents (including but not limited to methotrexate, azathioprine, mycophenolate mofetil, cyclophosphamide, cyclosporine or other steroid sparing agent) within 4 weeks prior to or during screening
    • Receiving systemic corticosteroids equivalent to prednisone > 10 mg/day or equivalent within 2 weeks prior to or during screening
    • Acute respiratory or systemic bacterial, viral, or fungal infection either during screening or prior to screening and not successfully resolved 4 weeks prior to screening visit
    • Participants with active or latent tuberculosis (confirmed within the 6 months prior to or during screening, by a positive screening test [interferon gamma release assay])
    • Resting oxygen saturation of < 89% using up to 4 L/min of supplemental oxygen at sea level and up to 6 L/min at altitude (>/= 5000 feet [1524 meters] above sea level) during screening
    • Class IV New York Heart Association chronic heart failure
    • Historical evidence of left ventricular ejection fraction < 35%
    • Presence of pulmonary hypertension that, in the investigator's opinion, would substantially limit the ability to comply with study requirements or may influence any of the safety or efficacy assessments included in the study
    • Cardiopulmonary rehabilitation program based on exercise training that has been completed within 8 weeks prior to screening or planned to start during the participant enrollment in this trial
    • History of smoking, alcohol or substance abuse disorder, or a malignancy
    • Previous treatment with PRM-151
    • Clinically significant abnormality on ECG during screening that, in the opinion of the investigator, may pose an additional risk in administering study drug to the participant including prolonged corrected QT interval > 450 ms (for men) or > 470 ms (for women) on ECG during screening based on the Fridericia correction formula
    • Clinically significant laboratory test abnormalities during screening (hematology, serum chemistry, and urinalysis) that, in the opinion of the investigator, may pose an additional risk in administering study drug to the participant
    • Pregnant or breastfeeding, or become pregnant during the study or within 8 weeks after the final dose of PRM-151
    • Women of childbearing potential (Only for participants enrolling in Japan)

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