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1 Study StatusRecruiting1 A 12-week study to investigate how the body handles alogabat once it is swallowed, how safe it is, and whether it could be effective in treating the symptoms of AS
Study to Investigate the Pharmacokinetics and Safety and to Provide Proof of Mechanism of Alogabat in Children and Adolescents Aged 5-17 Years With Angelman Syndrome (AS) With Deletion Genotype.
- Neurodevelopmental Disorder,
- Angelman Syndrome
- NCT05630066, BP41315, 2022-501844-14-00
2 Study StatusActive, not recruiting2 A Study To Investigate The Safety Of RO7248824 in Children With Angelman Syndrome And To Understand The Way The Body Processes The Investigational Therapy
A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7248824 in Participants With Angelman Syndrome (AS)
- Neurodevelopmental Disorder,
- Angelman Syndrome
- NCT04428281, BP41674, 2019-003787-48,RG6091
3 Study StatusCompleted3 A Study To Assess Distribution Of RO7248824 In The Central Nervous System Following Single Intrathecal Doses Of [89zr] Labeled RO7248824 In Healthy Male Participants
- Neurodevelopmental Disorder,
- Angelman Syndrome
- NCT04863794, BP41660