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1 Study StatusRecruiting1 A clinical trial to compare how safe and effective different doses of mosunetuzumab on its own or in combination with other treatments are in people with chronic lymphocytic leukemia that has not responded to, or has come back after previous treatments
A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a Combined Regimen of Mosunetuzumab and Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia
- Cancer,
- Leukemia,
- Chronic Lymphocytic Leukemia
- NCT05091424, BO43243, 2022-501876-24-00
2 Study StatusRecruiting2 A study to look at the effects of Venetoclax in patients with Chronic Lymphocytic Leukemia who are on stable cBTKi therapy
A Study to Evaluate the Effect of Venetoclax on Participants Receiving a Covalent Bruton's Tyrosine Kinase Inhibitor (cBTKi) for First-Line Chronic Lymphocytic Leukemia (1L CLL) to Achieve Deep Durable Remissions to Allow Off-Treatment Period.
- Cancer,
- Leukemia,
- Chronic Lymphocytic Leukemia
- NCT06524375, ML45219
3 Study StatusActive, not recruiting3 A clinical trial to compare venetoclax plus obinutuzumab with fludarabine, cyclophosphamide and rituximab or bendamustine and rituximab in people with chronic lymphocytic leukemia.
A Study to Compare the Efficacy and Safety of a Combined Regimen of Venetoclax and Obinutuzumab Versus Fludarabine, Cyclophosphamide, and Rituximab (FCR)/ Bendamustine And Rituximab (BR) in FIT Patients With Previously Untreated Chronic Lymphocytic Leukemia (CLL) Without DEL (17P) or TP53 Mutation
- Cancer,
- Leukemia,
- Chronic Lymphocytic Leukemia
- NCT04285567, CO41685, 2019-003327-37, 2023-504036-17-00
4 Study StatusActive, not recruiting4 A clinical trial to look at how safe different doses of mosunetuzumab are to give with or without atezolizumab in people with B-cell non-Hodgkin’s lymphoma or chronic lymphocytic leukaemia, how well they work, and how the body responds to and gets rid of the drugs
A Safety and Pharmacokinetic Study of BTCT4465A (Mosunetuzumab) as a Single Agent and Combined With Atezolizumab in Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)
- Cancer,
- Non Hodgkin Lymphoma (NHL),
- Lymphoma,
- Leukemia,
- Chronic Lymphocytic Leukemia
- NCT02500407, GO29781, 2023-506820-10-00
5 Study StatusActive, not recruiting5 A clinical study to compare obinutuzumab in combination with venetoclax and obinutuzumab in combination with chlorambucil in people with previously untreated chronic lymphocytic leukaemia who have other medical conditions
A Study to Compare the Efficacy and Safety of Obinutuzumab + Venetoclax (GDC-0199) Versus Obinutuzumab + Chlorambucil in Participants With Chronic Lymphocytic Leukemia
- Cancer,
- Leukemia,
- Chronic Lymphocytic Leukemia
- NCT02242942, BO25323, 2014-001810-24
6 Study StatusCompleted6 A Study of Obinutuzumab Evaluating Efficacy, Safety and Cost of Disease Management in Participants With Chronic Lymphocytic Leukemia and Comorbidities
- Cancer,
- Leukemia,
- Chronic Lymphocytic Leukemia
- NCT02915224, ML30133
7 Study StatusCompleted7 A Study to Evaluate the Benefit of Venetoclax Plus Rituximab Compared With Bendamustine Plus Rituximab in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)
- Cancer,
- Leukemia,
- Chronic Lymphocytic Leukemia
- NCT02005471, GO28667, 2013-002110-12
8 Study StatusCompleted8 A study to look at the safety and efficacy of obinutuzumab with bendamustine in people with a type of blood cancer called ‘chronic lymphocytic leukemia’ (GIBB)
A Study of Obinutuzumab + Bendamustine (BG) in Participants With Previously Untreated Chronic Lymphocytic Leukemia (CLL)
- Cancer,
- Leukemia,
- Chronic Lymphocytic Leukemia
- NCT02320487, ML29538
9 Study StatusCompleted9 Observational Study to Monitor Safety and Effectiveness of Obinutuzumab in Follicular Lymphoma or Previously Untreated Chronic Lymphocytic Leukemia
- Cancer,
- Non Hodgkin Lymphoma (NHL),
- Follicular Lymphoma,
- Leukemia,
- Chronic Lymphocytic Leukemia
- NCT03374137, ML30074
10 Study StatusCompleted10 Observational Study: Safety and Effectiveness of Obinutuzumab in Chronic Lymphocytic Leukemia in Argentina
- Cancer,
- Leukemia,
- Chronic Lymphocytic Leukemia
- NCT03059251, ML30187