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1 Study StatusRecruiting1 Frequency of Selected Single Nucleotide Polymorphisms in Huntington Disease Gene Expansion Carriers
- Neurodegenerative Disorder,
- Huntington Disease (HD)
- NCT06667414, WE45491
2 Study StatusRecruiting2 A clinical trial to look at how well RO7269162 works in people who are at risk of Alzheimer’s disease or who have mild cognitive impairment due to Alzheimer’s disease and how safe RO7269162 is at different doses
A Study to Evaluate the Safety and Biomarker Effects of RO7269162 in Participants at Risk for or at the Prodromal Stage of Alzheimer's Disease (AD)
- Neurodegenerative Disorder,
- Alzheimer's Disease (AD)
- NCT06402838, BP44745, 2023-506183-13-00
3 Study StatusActive, not recruiting3 A study to evaluate whether Prasinezumab can slow or halt disease progression in people with a recent diagnosis of Parkinson’s disease.
A Study to Evaluate the Efficacy of RO7046015 in Participants With Early Parkinson’s Disease (PASADENA)
- Neurodegenerative Disorder,
- Parkinson's Disease (PD)
- NCT03100149, BP39529, 2017-000087-15,2023-504472-24-00
4 Study StatusActive, not recruiting4 A study to evaluate the efficacy and safety of intravenous prasinezumab in participants with early Parkinson's disease
A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease
- Neurodegenerative Disorder,
- Parkinson's Disease (PD)
- NCT04777331, BN42358, 2020-004997-23
5 Study StatusActive, not recruiting5 Prospective Study to Assess Disease Activity and Biomarkers in Minority Participants With Relapsing Multiple Sclerosis (RMS) After Initiation and During Treatment With Ocrelizumab
- Autoimmune Disorder,
- Multiple Sclerosis (MS),
- Neurodegenerative Disorder,
- Relapsing Multiple Sclerosis (RMS)
- NCT04377555, ML42071
6 Study StatusActive, not recruiting6 A study to state how safe RO7126209 is at different doses and how the body processes RO7126209
Brainshuttle AD: A Multiple Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7126209 Following Intravenous Infusion in Participants With Prodromal or Mild to Moderate Alzheimer's Disease
- Neurodegenerative Disorder,
- Alzheimer's Disease (AD)
- NCT04639050, BP42155, 2020-002477-98,2023-509678-52-00
7 Study StatusActive, not recruiting7 A clinical trial to compare different doses of tominersen with a placebo in people with prodromal (very early subtle signs) and early manifest Huntington’s disease
GENERATION HD2. A Study to Evaluate the Safety, Biomarkers, and Efficacy of Tominersen Compared With Placebo in Participants With Prodromal and Early Manifest Huntington's Disease.
- Neurodegenerative Disorder,
- Huntington Disease (HD)
- NCT05686551, BN42489, Other
8 Study StatusActive, not recruiting8 A clinical trial to examine if an injection of ocrelizumab under the skin is a safe and effective alternative way of treating patients with multiple sclerosis (MS)
A Phase III, Non-Inferiority, Randomized, Open-Label, Parallel Group, Multicenter Study To Investigate The Pharmacokinetics, Pharmacodynamics, Safety And Radiological And Clinical Effects Of Subcutaneous Ocrelizumab Versus Intravenous Ocrelizumab In Patients With Multiple Sclerosis
- Autoimmune Disorder,
- Multiple Sclerosis (MS),
- Primary Progressive Multiple Sclerosis (PPMS),
- Neurodegenerative Disorder,
- Relapsing Multiple Sclerosis (RMS)
- NCT05232825, CN42097
9 Study StatusActive, not recruiting9 A study to evaluate the efficacy and safety of fenebrutinib compared with teriflunomide in adult patients with relapsing multiple sclerosis (FENhance 1)
A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)
- Autoimmune Disorder,
- Multiple Sclerosis (MS),
- Neurodegenerative Disorder,
- Relapsing Multiple Sclerosis (RMS)
- NCT04586010, GN41851, 2019-004857-10,2022-502609-14-00
10 Study StatusActive, not recruiting10 A study to evaluate the efficacy and safety of fenebrutinib compared with teriflunomide in adult patients with relapsing multiple sclerosis (FENhance 2)
Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)
- Autoimmune Disorder,
- Multiple Sclerosis (MS),
- Neurodegenerative Disorder,
- Relapsing Multiple Sclerosis (RMS)
- NCT04586023, GN42272, 2020-001168-28, 2022-502618-95-00