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1 Study StatusRecruiting1 A clinical trial to test CC-220 or CC-99282 in combination with mosunetuzumab, and CC-99282 in combination with glofitamab, in people with B-cell non-Hodgkin lymphoma.
A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma
- Cancer,
- Non Hodgkin Lymphoma (NHL)
- NCT05169515, CO43805, 2023-505185-28-00
2 Study StatusRecruiting2 A clinical trial to look at the safety and effectiveness of mosunetuzumab plus lenalidomide for treating follicular lymphoma
A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab + Lenalidomide (+Len), and the Safety, Tolerability, and Pharmacokinetics of SC Versus IV Mosunetuzumab + Len in Participants With Follicular Lymphoma
- Cancer,
- Non Hodgkin Lymphoma (NHL),
- Follicular Lymphoma
- NCT04246086, CO41942, 2023-507236-20-00
3 Study StatusRecruiting3 A clinical trial to look at how well glofitamab works on its own, and in combination with standard cancer chemotherapy plus immunotherapy in children and young adults with B-cell non-Hodgkin lymphoma (B-NHL) after one or multiple standard therapies have not worked
A Study to Evaluate Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma
- Cancer,
- Non Hodgkin Lymphoma (NHL),
- Mature B-Cell Non-Hodgkin Lymphoma,
- Mature B-Cell Lymphoma
- NCT05533775, CO43810
4 Study StatusRecruiting4 A clinical trial to compare how well glofitamab on its own works versus standard treatment in people with mantle cell lymphoma that has come back after or has not responded to treatment
A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma
- Cancer,
- Non Hodgkin Lymphoma (NHL),
- Lymphoma
- NCT06084936, GO43878, 2023-503206-37-00
5 Study StatusRecruiting5 A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
- Cancer,
- Non Hodgkin Lymphoma (NHL),
- Lymphoma
- NCT06624085, GO44900
6 Study StatusRecruiting6 A clinical trial to look at whether RO7227166 combined with another treatment (either obinutuzumab or glofitamab) is safe and effective at different doses for patients with relapsed or refractory B-cell non-Hodgkin’s lymphoma
A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-Tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab and in Combination With Glofitamab Following a Pre-Treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma
- Cancer,
- Non Hodgkin Lymphoma (NHL),
- Lymphoma
- NCT04077723, BP41072, 2019-000416-28,2022-502616-37-00
7 Study StatusRecruiting7 A clinical trial to compare glofitamab plus Pola-R-CHP with Pola-R-CHP alone in people with untreated large B-cell lymphoma
An Open-Label Study Comparing Glofitamab and Polatuzumab Vedotin + Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone Versus Pola-R-CHP in Previously Untreated Patients With Large B-Cell Lymphoma
- Cancer,
- Non Hodgkin Lymphoma (NHL),
- Diffuse Large B-Cell Lymphoma (DLBCL)
- NCT06047080, GO44145
8 Study StatusRecruiting8 A study to understand the optimization of the cytokine release syndrome profile for glofitamab along with gemcitabine plus oxaliplatin in patients with relapsed/refractory diffuse large B-cell lymphoma
A Study to Evaluate the Optimization of the Cytokine Release Syndrome Profile for Glofitamab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
- Cancer,
- Non Hodgkin Lymphoma (NHL),
- Diffuse Large B-Cell Lymphoma (DLBCL)
- NCT06806033, GO45434, 2024-516791-15-00
9 Study StatusActive, not recruiting9 A clinical study for people with B-cell non‑Hodgkin lymphoma that looks at how safe and how well mosunetuzumab works when given in combination with polatuzumab vedotin
A Study to Evaluate the Safety and Efficacy of Mosunetuzumab (BTCT4465A) in Combination With Polatuzumab Vedotin in B-Cell Non-Hodgkin Lymphoma
- Cancer,
- Non Hodgkin Lymphoma (NHL),
- B-cell Non-Hodgkin Lymphoma
- NCT03671018, GO40516, 2023-506986-74-00
10 Study StatusActive, not recruiting10 A clinical trial to look at how well glofitamab plus R-CHOP (rituximab plus cyclophosphamide, doxorubicin, vincristine and prednisone) worked in people with ctDNA high-risk diffuse large B-cell lymphoma (DLBCL)
A Study to Evaluate the Safety and Efficacy of Glofitamab in Combination With Rituximab (R) Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) in Circulating Tumor (ct)DNA High-Risk Patients With Untreated Diffuse Large B-Cell Lymphoma
- Cancer,
- Non Hodgkin Lymphoma (NHL),
- Diffuse Large B-Cell Lymphoma (DLBCL),
- Lymphoma
- NCT04980222, GO43075