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1 Study StatusRecruiting1 A study to evaluate the safety, tolerability, processing by the body and mechanism of action of multiple doses of ralmitaront with a single dose of risperidone administered to healthy participants
A single-center, single-sequence, open-label, two-period study to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamic effects of the combination of multiple doses of ralmitaront with a single dose of risperidone in healthy subjects
- Psychiatric Disorder,
- Schizophrenia
- BP43026
2 Study StatusRecruiting2 A Study of Atezolizumab Compared With Platinum Doublet Chemotherapy for PD-L1 Highly Expressed, Chemotherapy-Naïve Patients With Stage IV Non-Squamous or Squamous Non-Small Cell Lung Cancer
- Cancer,
- Lung Cancer,
- Non-Small Cell Lung Cancer (NSCLC)
- NCT05047250, ML42606
3 Study StatusRecruiting3 A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of NXT007 in Persons With Severe or Moderate Hemophilia A
- Hemophilia,
- Hemophilia A
- NCT05987449, WP44714, 2023-503906-35-00
4 Study StatusRecruiting4 A clinical trial to test CC-220 or CC-99282 in combination with mosunetuzumab, and CC-99282 in combination with glofitamab, in people with B-cell non-Hodgkin lymphoma.
A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma
- Cancer,
- Non Hodgkin Lymphoma (NHL)
- NCT05169515, CO43805, 2023-505185-28-00
5 Study StatusRecruiting5 A study to look at how safe and well inavolisib works together with paclitaxel at different doses. The study will also try to understand how the body reacts to this treatment in people with certain cancers that have grown or spread
A Phase Ib, open-label, dose-escalation and dose-expansion study evaluating the safety, tolerability, pharmacokinetics, and preliminary antitumor activity of inavolisib in combination with paclitaxel and with or without targeted therapies in patients with locally advanced or metastatic solid tumors
- Cancer,
- Head and Neck Cancer,
- Squamous Cell Carcinoma of the Head and Neck (SCCHN),
- Breast Cancer,
- Solid Tumors,
- Ovarian Cancer
- CO42800, 2023-506745-33-00
6 Study StatusRecruiting6 A clinical trial to look at how the body processes satralizumab in children with neuromyelitis optica spectrum disorder (NMOSD)
A Study To Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, And Pharmacodynamics Of Satralizumab In Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD)
- Autoimmune Disorder,
- Neuromyelitis optica spectrum disorder (NMOSD)
- NCT05199688, WN41733, 2019-004092-39
7 Study StatusRecruiting7 An observational study to describe the fertility journey of Evrysdi (risdiplam)-treated adult male individuals with spinal muscular atrophy
An observational study to look at the effects of Evrysdi (risdiplam) on fertility in adult male with spinal muscular atrophy
- Muscle And Peripheral Nerve Disease,
- Spinal Muscular Atrophy (SMA)
- ML44914
8 Study StatusRecruiting8 A clinical trial to compare how safe and effective different doses of mosunetuzumab on its own or in combination with other treatments are in people with chronic lymphocytic leukemia that has not responded to, or has come back after previous treatments
A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a Combined Regimen of Mosunetuzumab and Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia
- Cancer,
- Leukemia,
- Chronic Lymphocytic Leukemia
- NCT05091424, BO43243, 2022-501876-24-00
9 Study StatusRecruiting9 A Study Evaluating the Safety, Pharmacokinetics, and Activity of the Combination of Cevostamab and Elranatamab in Participants With Relapsed or Refractory Multiple Myeloma (R/R MM)
- Cancer,
- Multiple Myeloma,
- Relapsed or Refractory Multiple Myeloma
- NCT05927571, GO43979, 2023-504657-13-00
10 Study StatusRecruiting10 A study to look at the effects of Venetoclax in patients with Chronic Lymphocytic Leukemia who are on stable cBTKi therapy
A Study to Evaluate the Effect of Venetoclax on Participants Receiving a Covalent Bruton's Tyrosine Kinase Inhibitor (cBTKi) for First-Line Chronic Lymphocytic Leukemia (1L CLL) to Achieve Deep Durable Remissions to Allow Off-Treatment Period.
- Cancer,
- Leukemia,
- Chronic Lymphocytic Leukemia
- NCT06524375, ML45219