A clinical trial to look at the long-term safety and effects of faricimab for people with diabetic macular edema (RHONE-X)

A Study to Evaluate the Long-Term Safety and Tolerability of Faricimab in Participants With Diabetic Macular Edema

  • Eye Disorder
  • Diabetic Macular Edema
Please note that the recruitment status of the study at your site may differ from the overall study status because some study sites may recruit earlier than others.
Study Status:

Completed

This study runs in
Cities
  • Aalborg
  • aan
  • Abilene
  • Aiea
  • Albacete
  • Albany
  • Albuquerque
  • alicante--alacant-
  • Amagasaki
  • Ankara
  • Arizona
  • Asahikawa
  • Augusta
  • Aurora
  • Austin
  • Bakersfield
  • Baltimore
  • Barcelona
  • Beachwood
  • Belfast
  • Bellaire
  • Beverly Hills
  • Bielsko-Biała
  • Binningen
  • Boisbriand
  • Bordeaux
  • Boston
  • Bradford
  • Braga
  • Budapest
  • Buenos Aires
  • Burjasot
  • Burlington
  • Bydgoszcz
  • Bytom
  • Calgary
  • Camberley
  • Campbell
  • Canterbury
  • Carmel
  • Chang Wat Chiang Mai
  • Charlotte
  • Charlottesville
  • Chattanooga
  • Cheboksary
  • Chesterfield
  • Chevy Chase
  • Cincinnati
  • Ciudad de México
  • Cleveland
  • Coimbra
  • Colorado Springs
  • Columbus
  • Créteil
  • czelad_
  • Dallas
  • Debrecen
  • Dresden
  • Dublin
  • East Melbourne
  • Edina
  • Edison
  • Edmond
  • Firenze
  • Fort Lauderdale
  • Fort Myers
  • Freiburg im Breisgau
  • Fresno
  • Fukuoka
  • Fullerton
  • Gdańsk
  • Germantown
  • Gliwice
  • Gloucester
  • Goiás
  • Grand Rapids
  • Graz
  • Great Yarmouth
  • Greenville
  • Hachioji
  • Hagerstown
  • Haifa
  • Halifax
  • Hannover
  • Harlingen
  • Hauppauge
  • Hickory
  • Hlavní město Praha
  • Homburg
  • Hong Kong Island
  • Irkutsk
  • İstanbul
  • İzmir
  • Jerusalem
  • Kashihara
  • Kazan
  • Kocaeli
  • Konya
  • Košický kraj
  • Kraków
  • Krung Thep Maha Nakhon
  • Královéhradecký kraj
  • Kumamoto
  • Kurume
  • Kyoto
  • L'Hospitalet de Llobregat
  • Ladson
  • Lakewood
  • Las Palmas de Gran Canaria
  • Leeds
  • Lenexa
  • Lexington
  • Lima
  • Linz
  • Lisboa
  • Liverpool
  • Lombardia
  • London
  • Los Angeles
  • Lynchburg
  • Madison
  • Madrid
  • Magdeburg
  • Majadahonda
  • Manchester
  • Marietta
  • Melbourne
  • Mendoza
  • Mesa
  • Milano
  • Millcreek
  • Mitaka
  • Mito
  • Miyazaki
  • Morgantown
  • Moskva
  • Mountain View
  • München
  • Münster
  • Nagakute
  • Nagoya
  • Nantes
  • Nashville
  • Nedlands
  • negrar-di-valpolicella
  • New York
  • Newcastle upon Tyne
  • Norfolk
  • Northfield
  • Novosibirsk
  • Oak Forest
  • Oakland
  • Oceanside
  • Osaka
  • Ostrava
  • Otsu
  • Oviedo
  • Palm Beach Gardens
  • Palm Desert
  • Pamplona
  • Paris
  • Pasadena
  • Pennsylvania
  • Pensacola
  • Perugia
  • Petah Tikva
  • Philadelphia
  • Phoenix
  • Pisa
  • Plantation
  • Pompano Beach
  • Portland
  • Porto Alegre
  • Poway
  • Pécs
  • Redlands
  • Rehovot
  • Reno
  • Richmond
  • Rochester
  • Roma
  • Rosario
  • Roskilde
  • Rowville
  • Royal Oak
  • Rybnik
  • Rzeszów
  • Sacramento
  • Saint-Cyr-sur-Loire
  • Sakura
  • Salina
  • Salt Lake City
  • San Antonio
  • San Francisco
  • San Isidro
  • Sankt-Peterburg
  • Sant Cugat del Vallès
  • Santa Ana
  • Santa Barbara
  • Santa Catarina
  • Santa Maria
  • Santiago de Compostela
  • Santiago de Querétaro
  • Santiago de Surco
  • Sapporo
  • Seongnam-si
  • Seoul
  • Shinjuku City
  • Shirley
  • Singapore
  • Slingerlands
  • Sofia
  • sokolov-1
  • Southampton
  • Southlake
  • Springfield
  • St. Petersburg
  • Strathfield
  • Sunderland
  • Sydney
  • Szeged
  • Szombathely
  • São Paulo
  • Taipei City
  • Tallahassee
  • Tampa
  • Taoyuan City
  • Tarnowskie Góry
  • Teaneck
  • Tel Aviv-Yafo
  • The Woodlands
  • Tokorozawa
  • Toronto
  • Towson
  • Traverse City
  • Trenčiansky kraj
  • Tsu
  • Tucson
  • Tyler
  • Ufa
  • uxbridge
  • Valladolid
  • València
  • Walnut Creek
  • Warszawa
  • Washington
  • Waterford
  • West Des Moines
  • west-columbia
  • Westmead
  • Wichita
  • Wien
  • Willow Park
  • Winston-Salem
  • Worcester
  • Wrocław
  • Würzburg
  • Zalaegerszeg
  • Écully
  • Žilinský kraj
  • 横浜市
Trial Identifier:

NCT04432831 2020-000402-29 GR41987

  • ?Intersec Research and Technology Complex Eye Microsurgery n a Fyodorov Novosibirsk Branch

    149 Ulitsa L'va Tolstogo630008NovosibirskRussia
  • ?Intersec. Research and Technology Complex ?Eye Microsurgery? n a Fyodorov Irkutsk branch

    3 Ulitsa Bogdana Khmel'nitskogo664000IrkutskRussia
  • Aalborg Universitetshospital; Øjenafdelingen

    10 Mølleparkvej9000AalborgDenmark
  • AIBILI - Association for Innovation and Biomedical Research on Light

    3000-548CoimbraPortugal
  • Aichi Medical University Hospital

    480-1195NagakuteJapan
  • Ankara Baskent University Medical Faculty; Department of Ophthalmology

    06490AnkaraTürkiye
  • Ankara University Medical Faculty; Department of Ophthalmology

    12 Mamak Cd.06620AnkaraTürkiye
  • Arizona Retina and Vitreous Consultants

    3840 N 16th St85016PhoenixUnited States
  • Asahikawa Medical University Hospital

    078-8510AsahikawaJapan
  • Asan Medical Center

    05505SeoulSouth Korea
  • Assoc Retinal Consultants PC

    3555 W 13 Mile Rd48073Royal OakUnited States
  • Associated Retinal Consultants

    1179 E Paris Ave SE49546Grand RapidsUnited States
  • Associated Retinal Consultants, P.C.

    860 E Front St49686Traverse CityUnited States
  • Augenabteilung am St. Franziskus-Hospital

    74 Hohenzollernring48145MünsterGermany
  • Austin Clinical Research LLC

    9707 Anderson Mill Rd78750AustinUnited States
  • Austin Retina Associates

    AustinUnited States
  • AXON Clinical

    140 00Hlavní město PrahaCzechia
  • Azienda Ospedaliera di Perugia Ospedale S. Maria Della Misericordia; Clinica Oculistica

    3 Piazzale Giorgio Menghini06129PerugiaItaly
  • Azienda Ospedaliero-Universitaria Careggi; S.O.D. Oculistica

    3 Largo Giovanni Alessandro Brambilla50134FirenzeItaly
  • Bajcsy-Zsilinszky Hospital

    89-91 Maglódi út1106BudapestHungary
  • Barnet Dulaney Perkins Eye Center

    5250 E Southern Ave85206MesaUnited States
  • Bay Area Retina Associates

    365 Lennon Ln94598Walnut CreekUnited States
  • Beetham Eye Institute, Joslin Diabetes Center

    1 Joslin Pl02215BostonUnited States
  • Belfast Health and Social Care Trust, ROYAL VICTORIA HOSPITAL

    274 Grosvenor RdBT12 6BABelfastUnited Kingdom
  • Beyoglu Goz Training and Research Hospital; Department Of Ophthalmology

    No:2 Bereketzade Cami Sk.34421İstanbulTürkiye
  • Botelho Hospital da Visao

    2958 R. Dois de Setembro89052-504Santa CatarinaBrazil
  • Bradford Royal Infirmary

    BD9 6RJBradfordUnited Kingdom
  • Budapest Retina Associates Kft.

    76 Váci út1133BudapestHungary
  • Calgary Retina Consultants

    5340 1 St SWT2H 0C8CalgaryCanada
  • California Eye Specialists Medical group Inc.

    2619 E Colorado Blvd91107PasadenaUnited States
  • California Retina Consultants

    525 E Micheltorena St93103Santa BarbaraUnited States
  • California Retina Consultants - Santa Maria

    116 Palisade Dr93454Santa MariaUnited States
  • California Retina Consultants.

    5555 Business Park S93309BakersfieldUnited States
  • Caminomed

    3 Wyszyńskiego42-600Tarnowskie GóryPoland
  • Capital Region Retina

    12206AlbanyUnited States
  • CEMAPE - Centro Médico

    São PauloBrazil
  • Centre For Eye Research Australia

    200 Victoria Parade3002East MelbourneAustralia
  • Centre Hospitalier Universitaire de Bordeaux Hopital Pellegrin

    33000BordeauxFrance
  • Centres Ophtalmologique St Exupéry; Ophtalmologie

    37540Saint-Cyr-sur-LoireFrance
  • Centro Brasileiro de Cirurgia

    2-1198 Av. T-274210-010GoiásBrazil
  • Centro de Oftalmologia Barraquer; Servicio Oftalmologia

    314 carr. de Muntaner08021BarcelonaSpain
  • Centro Oftalmológico Mira, S.C

    #35 C. Taxco06760Ciudad de MéxicoMexico
  • Centro Oftalmólogos Especialistas

    RosarioArgentina
  • Centrum Medyczne UNO-MED

    19 w Józefa Dietla31-070KrakówPoland
  • Centrum Zdrowia MDM

    4a Inflancka00-189WarszawaPoland
  • Chang Gung Medical Foundation - Linkou; Ophthalmology

    259號 Wenhua 1st Rd333Taoyuan CityTaiwan
  • Char Eye Ear &Throat Assoc

    28217CharlotteUnited States
  • Charles Retina Institute

    1432 Kimbrough Rd38138GermantownUnited States
  • Charleston Neuroscience Inst

    9551 US-7829456LadsonUnited States
  • Chi De Creteil; Ophtalmologie

    40 Av. de Verdun94000CréteilFrance
  • CHU Nantes - Hôtel Dieu; Ophthalmology

    1 Pl. Alexis-Ricordeau44000NantesFrance
  • Cincinnati Eye Institute

    45242CincinnatiUnited States
  • Cleveland Clinic Foundation; Cole Eye Institute

    ClevelandUnited States
  • Clinic Optimed

    8 Ulitsa 50 Let Sssr450083UfaRussia
  • Clinica Baviera; Servicio Oftalmologia

    20 P.º de la Castellana28046MadridSpain
  • Clinica Universitaria de Navarra; Servicio de Oftalmologia

    36 Av. de Pío XII31008PamplonaSpain
  • Clinics of Eye Diseases, LLC

    420066KazanRussia
  • Colorado Retina Associates, PC

    255 S Routt Way80228LakewoodUnited States
  • Complejo Hospitalario de Navarra; Servicio de oftalmologia

    3 C. de Irunlarrea31008PamplonaSpain
  • Complejo Hospitalario Universitario Albacete; Servicio de oftalmologia

    37 C. Hermanos Falco02008AlbaceteSpain
  • Cumberland Valley Retina PC

    1150 Opal Ct21740HagerstownUnited States
  • Debreceni Egyetem Klinikai Kozpont; Szemeszeti Klinika

    98 Nagyerdei krt.4032DebrecenHungary
  • Dobry Wzrok Sp Z O O

    1b Kliniczna80-402GdańskPoland
  • East Bay Retina Consultants

    3300 Telegraph Ave94609OaklandUnited States
  • East Kent Hospitals University NHS Foundation Trust

    CT1 3NGCanterburyUnited Kingdom
  • Ege University Medical Faculty; Department of Ophthalmology

    35100İzmirTürkiye
  • Emerson Clinical Research Institute

    508 Kennedy St NW20011WashingtonUnited States
  • Espaco Medico Coimbra

    37 R. Câmara Pestana3030-163CoimbraPortugal
  • Eszak-Pesti Centrumkorhaz - Honvedkorhaz; Szemeszet

    44 Róbert Károly körút1134BudapestHungary
  • Eye Care Assoc of East Texas

    2440 E 5th St75701TylerUnited States
  • Eye Medical Center

    1360 E Herndon Ave93720FresnoUnited States
  • Faculdade de Medicina do ABC - FMABC

    2000 Av. Lauro Gomes09060-870São PauloBrazil
  • Faculty Hospital Kralovske Vinohrady; Ophthalmology clinic

    Hlavní město PrahaCzechia
  • Faculty Hospital Ostrava; Ophthalmology clinic

    OstravaCzechia
  • Fakultna nemocnica s poliklinikou Zilina; Ocne oddelenie

    1741 Vojtecha Spanyola010 01Žilinský krajSlovakia
  • Fakultna nemocnica Trencin Ocna klinika

    33 Legionárska911 01Trenčiansky krajSlovakia
  • Fisabio-Ofalmologia Medica; Servicio de Oftalmología

    21 Av. de Catalunya46020ValènciaSpain
  • Florida Eye Associates

    32901MelbourneUnited States
  • FN Hradec Králové, O?ní klinika; Ophthalmology clinic

    581 Sokolská500 05Královéhradecký krajCzechia
  • Fondazione G.B. Bietti Per Lo Studio E La Ricerca in Oftalmologia-Presidio Ospedaliero Britannico

    6 Via Santo Stefano Rotondo00184RomaItaly
  • Fondazione Irccs Ca' Granda Ospedale Maggiore Policlinico-Clinica Regina Elena;U.O.C Oculistica

    6 Via Manfredo Fanti20122MilanoItaly
  • Fort Lauderdale Eye Institute

    850 S Pine Island Rd33324PlantationUnited States
  • Foundation for Vision Research

    5030 Cascade Rd SE49546Grand RapidsUnited States
  • Frimley Park Hospital

    GU16 7UJCamberleyUnited Kingdom
  • FSBI ?Scientific Research Institute of Eye Diseases? of Russian Academy of medical Sciences

    11А Ulitsa Rossolimo119021MoskvaRussia
  • Fundacion Zambrano

    1023Buenos AiresArgentina
  • Gabinet Okulistyczny Prof Edward Wylegala

    8 Rynek40-003czelad_Poland
  • Ganglion Medial Center

    7621PécsHungary
  • Georgia Retina PC

    MariettaUnited States
  • Gloucestershire Hospitals NHS Foundation Trust

    GL1 2ELGloucesterUnited Kingdom
  • Graystone Eye

    2424 Century Pl SE28602HickoryUnited States
  • Grupo Laser Vision

    RosarioArgentina
  • Hacettepe University Medical Faculty; Department of Ophthalmology

    AnkaraTürkiye
  • Hadassah MC; Ophtalmology

    JerusalemIsrael
  • Hanusch Krankenhaus; Abteilung für Augenkrankheiten mit Augen-Tagesklinik

    30 Heinrich-Collin-Straße1140WienAustria
  • Hayashi Eye Hospital

    812-0011FukuokaJapan
  • Hillingdon Hospital

    UB8 3NNuxbridgeUnited Kingdom
  • Hokkaido University Hospital

    060-8648SapporoJapan
  • Hong Kong Eye Hospital; CUHK Eye Centre

    147K Argyle StTorontoHong Kong
  • Hopital Lariboisiere; Ophtalmologie

    2 Rue Ambroise Paré75010ParisFrance
  • Hosp de Olhos de Sorocaba

    18031-060São PauloBrazil
  • Hospital Clinic de Barcelona; Consultas Externas Oftalmologia

    170 C. de Villarroel08036BarcelonaSpain
  • Hospital das Clinicas - FMUSP

    225 R. Dr. Ovídio Pires de Campos05403-010São PauloBrazil
  • Hospital das Clinicas - UFRGS

    Porto AlegreBrazil
  • Hospital de Braga; Servico de Oftalmologia

    4710-243BragaPortugal
  • Hospital de la Ceguera APEC

    46 Calle Vicente García Torres04030Ciudad de MéxicoMexico
  • Hospital de Olhos de Aparecida - HOA

    S/n Av. Dom Abel Ribeiro74980-010GoiásBrazil
  • Hospital de Santa Creu I Sant Pau; Servicio de Oftalmologia

    89 C/ de Sant Quintí08025BarcelonaSpain
  • Hospital de Santa Maria; Servico de Oftalmologia

    MB Av. Prof. Egas Moniz1649-028LisboaPortugal
  • Hospital dos de maig; servicio de oftalmologia

    301 C. del dos de Maig08025BarcelonaSpain
  • Hospital General de Catalunya

    1 Carrer de Pedro i Pons08195Sant Cugat del VallèsSpain
  • Hospital Universitario de Bellvitge

    s/n Carrer de la Feixa Llarga08907L'Hospitalet de LlobregatSpain
  • Hospital Universitario de Gran Canaria; Servicio de oftalmologia

    s/n C. Pl. Barranco de la Ballena35010Las Palmas de Gran CanariaSpain
  • Hospital Universitario Puerta de Hierro

    1 C. Joaquín Rodrigo28222MajadahondaSpain
  • Hospital Universitario Rio Hortega; Servicio de Oftalmologia

    2 C. Dulzaina47012ValladolidSpain
  • Hyogo Prefectural Amagasaki General Medical Center (Hyogo AGMC)

    660-8550AmagasakiJapan
  • Ideta Eye Hospital

    860-0027KumamotoJapan
  • Institut De L'Oeil Des Laurentides

    6110 R. Doris-LussierJ7H 0E8BoisbriandCanada
  • Instituto de la retina del Bajio

    76180Santiago de QuerétaroMexico
  • Instituto Oftalmologico Fernandez Vega; Servicio de oftalmologia

    34 Av. Doctores Fernández Vega33012OviedoSpain
  • Instituto Oftalmologico Gomez Ulla; Servicio de Oftalmologia

    3 Rúa de Maruja Mallo15706Santiago de CompostelaSpain
  • Intersec Research and Technology Complex ?Eye Microsurgery? n.a. S.N. Fyodorov; Cheboksary Branch

    CheboksaryRussia
  • Irccs Ospedale San Raffaele;U.O. Oculistica

    60 Via Olgettina20132LombardiaItaly
  • Island Retina

    60 Northern Blvd11967ShirleyUnited States
  • Ivey Eye Institute

    1255 Western RdN6G 0N1LondonCanada
  • James Paget University Hospitals NHS Foundation Trust

    NR31 6LAGreat YarmouthUnited Kingdom
  • Johns Hopkins Med; Wilmer Eye Inst

    1800 Orleans St21287BaltimoreUnited States
  • Kaplan Medical Center; Ophtalmology

    1 Derech PasternakRehovotIsrael
  • Kepler Universitätskliniken GmbH - Med Campus III; Abt. für Augenheilkunde

    9 Krankenhausstraße4020LinzAustria
  • King Chulalongkorn Memorial Hospital; Ophthalmology Department

    1873 Thanon Rama IV10330Krung Thep Maha NakhonThailand
  • Kings College Hospital

    SE5 9RSLondonUnited Kingdom
  • Kitano Hospital

    530-8480OsakaJapan
  • Kliniczny Szpital Wojewodzki nr 1 im. F. Chopina; Klinika Okulistyki

    2 Szopena35-055RzeszówPoland
  • Klinikum rechts der Isar der TU München; Augenklinik

    22 Ismaninger Str.81675MünchenGermany
  • Kocaeli Üniversitesi T?p Fakültesi; Department of Ophthalmology

    41001KocaeliTürkiye
  • Kozawa eye hospital and diabetes center

    310-0845MitoJapan
  • Kurume University Hospital

    830-0011KurumeJapan
  • Kyorin University Hospital

    181-8611MitakaJapan
  • Kyoto University Hospital

    606-8507KyotoJapan
  • Kyung Hee University Hospital

    130-050SeoulSouth Korea
  • LKH-Univ.Klinikum Graz; Universitäts-Augenklinik

    1 Auenbruggerpl.8036GrazAustria
  • LMU Klinikum der Universität, Augenklinik

    8A Pettenkoferstraße80336MünchenGermany
  • Long Is. Vitreoretinal Consult

    200 Motor Pkwy11788HauppaugeUnited States
  • Mácula D&T

    186 Av. Guardia Civil15036San IsidroPeru
  • Macula Retina Consultores

    108 Calle Sur 13201120Ciudad de MéxicoMexico
  • Maharaj Nakorn ChiangMai Hospital; Ophthalmology Department

    50200Chang Wat Chiang MaiThailand
  • Maine Eye Center

    161 Marginal Way04101PortlandUnited States
  • Manchester Royal Eye Hospital

    M13 9WLManchesterUnited Kingdom
  • Markusovszky Egyetemi Oktatokorhaz ; SZEMESZET; Intezeti Gyogyszertar

    5 Markusovszky Lajos u.9700SzombathelyHungary
  • Medical Center for Eye Health ? Focus Ltd

    1303SofiaBulgaria
  • Medical Center Ophthalmology Associates

    9157 Huebner Rd78240San AntonioUnited States
  • Medical Military Academy n.a S.M.Kirov

    194044Sankt-PeterburgRussia
  • Medizinische Hochschule Hannover, Klinik für Augenheilkunde

    1 Carl-Neuberg-Straße30625HannoverGermany
  • Medizinische Universität Wien; Universitätsklinik für Augenheilkunde und Optometrie

    18-20 Währinger Gürtel1090WienAustria
  • Mid Atlantic Retina - Wills Eye Hospital

    840 Walnut St19107PhiladelphiaUnited States
  • Mid-Atlantic Retina

    840 Walnut St19107PhiladelphiaUnited States
  • Midwest Eye Institute

    10300 Illinois St46290CarmelUnited States
  • Midwest Retina

    6655 Post Rd43016DublinUnited States
  • Midwest Vision Research Foundation

    63017ChesterfieldUnited States
  • Mie University Hospital

    514-8507TsuJapan
  • Moorfields Eye Hospital NHS Foundation Trust

    162 City RdEC1V 2PDLondonUnited Kingdom
  • Nagoya City University Hospital

    467-8602横浜市Japan
  • Nagoya University Hospital

    466-8560横浜市Japan
  • Nara Medical University Hospital

    634-8522KashiharaJapan
  • National Defense Medical College Hospital

    359-0042TokorozawaJapan
  • National Ophthalmic Research Institute

    33912Fort MyersUnited States
  • National Taiwan University Hospital; Ophthalmology

    7號 Zhongshan S Rd100Taipei CityTaiwan
  • National University Hospital; Ophthalmology Department

    5 Lower Kent Ridge Rd119074SingaporeSingapore
  • Nemocnica s poliklinikou Trebišov, a.s.

    075 01Košický krajSlovakia
  • Nemocnice Sokolov

    545 Slovenská356 01sokolov-1Czechia
  • New York University

    10012New YorkUnited States
  • NJRetina

    98 James St08820EdisonUnited States
  • Northern California Retina Vitreous Associates

    2495 Hospital Dr94040Mountain ViewUnited States
  • OFTALMIKA Sp. z o.o

    45 Kazimierza Pułaskiego85-619BydgoszczPoland
  • Oftalmolaser

    1953 Av. Primavera15023Santiago de SurcoPeru
  • Oftalmos

    1832 Av. CórdobaC1120aanArgentina
  • Oftalvist Valencia

    1 Av. de la Ilustración46100BurjasotSpain
  • Oftar

    MendozaArgentina
  • Ophthalmic Cons of Long Island

    11572OceansideUnited States
  • Ophthalmic Consultants of Boston

    50 Staniford St02114BostonUnited States
  • Optimum Profesorskie Centrum Okulistyki

    30 Cienista80-809GdańskPoland
  • Optomed Sp. z o.o.

    13b Miejska44-200RybnikPoland
  • Orange County Retina Med Group

    999 N Tustin Ave92705Santa AnaUnited States
  • Organizacion Medica de Investigacion

    725 UruguayC1015Buenos AiresArgentina
  • Osaka Metropolitan University Hospital

    545-0051OsakaJapan
  • Ospedale Classificato Equiparato Sacro Cuore ? Don Calabria; Presso Ufficio Cassa

    4 Viale Luigi Rizzardi37024negrar-di-valpolicellaItaly
  • Osrodek Chirurgii Oka prof. Zagorskiego Rzeszow

    8 Stanisława Moniuszki35-017RzeszówPoland
  • Palmetto Retina Center

    124 Sunset Ct29169west-columbiaUnited States
  • Pentagram Eye Hospital (Medical Center "Pentagram")

    109 ul. "Vranya"1309SofiaBulgaria
  • Peterfy Sandor utcai Korhaz-Rendelointezet es Baleseti Kozpont, Szemeszet KR

    BudapestHungary
  • Piedmont Eye Center

    116 Nationwide Dr24502LynchburgUnited States
  • Pole Vision Val d'Ouest; Ophtalmologie

    39 Chem. de la Vernique69130ÉcullyFrance
  • Poradnia Okulistyczna i Salon Optyczny w Gliwicach- PRYZMAT

    70 Tarnogórska44-100GliwicePoland
  • Prairie Eye & LASIK Center / Prairie Retina Center

    2800 Montaluma Dr62704SpringfieldUnited States
  • QEII - HSC Department of Ophthalmology

    1276 South Park StB3H 2Y9HalifaxCanada
  • Queen Mary Hospital; Department of Ophthalmology

    Hong Kong IslandHong Kong
  • Rabin MC; Ophtalmology

    39 Zeev Jabotinsky St4941492Petah TikvaIsrael
  • Rajavithi Hospital; Ophthalmology Department

    2 Phaya Thai Rd10400Krung Thep Maha NakhonThailand
  • Rambam Medical Center; Opthalmology

    8 HaAliya HaShniya St3109601HaifaIsrael
  • Rand Eye

    5 W Sample Rd33064Pompano BeachUnited States
  • Retina & Vitreous of Texas

    6565 W Loop S77401BellaireUnited States
  • Retina Assoc of Cleveland Inc

    24075 Commerce Park Rd44122BeachwoodUnited States
  • Retina Associates

    8600 Quivira Rd66215LenexaUnited States
  • Retina Associates of Florida, LLC

    602 S MacDill Ave33609TampaUnited States
  • Retina Associates of Kentucky

    120 N Eagle Creek Dr40509LexingtonUnited States
  • Retina Associates of NJ

    07666TeaneckUnited States
  • Retina Associates of Utah, PLLC

    84107MillcreekUnited States
  • Retina Associates of Western New York

    160 Sawgrass Dr14620RochesterUnited States
  • Retina Associates Southwest PC

    2121 N Craycroft Rd85712TucsonUnited States
  • Retina Care Specialists

    3399 PGA Boulevard33410Palm Beach GardensUnited States
  • Retina Center of Texas

    305 Morrison Park Dr76092SouthlakeUnited States
  • Retina Consultants Of Carolina

    1126 Grove Rd29605GreenvilleUnited States
  • Retina Consultants of Hawaii

    98-1079 Moanalua Rd96701AieaUnited States
  • Retina Consultants of Orange County

    301 W Bastanchury Rd92835FullertonUnited States
  • Retina Consultants of Southern

    2770 N Union Blvd80909Colorado SpringsUnited States
  • Retina Consultants of Southern California

    1895 Orange Tree Ln92374RedlandsUnited States
  • Retina Consultants of Texas

    77384The WoodlandsUnited States
  • Retina Consultants, San Diego

    12630 Monte Vista Rd92064PowayUnited States
  • Retina Group of Florida

    6333 N Federal Hwy33308Fort LauderdaleUnited States
  • Retina Group of New England

    174 Cross Rd06385WaterfordUnited States
  • Retina Group of Washington

    5454 Wisconsin Ave20815Chevy ChaseUnited States
  • Retina Institute of Virginia

    8720 Stony Point Pkwy23235RichmondUnited States
  • Retina Northwest

    5440 SW Westgate Dr97221PortlandUnited States
  • Retina Res Institute of Texas

    79606AbileneUnited States
  • Retina Specialists

    6569 MD-13921204TowsonUnited States
  • Retina Specialists Victoria

    1091 Stud Rd3178RowvilleAustralia
  • Retina Specialty Institute

    5150 N Davis Hwy32503PensacolaUnited States
  • Retina Vit Surgeons/Central NY

    200 Greenfield Pkwy13088SalinaUnited States
  • Retina Vitreous Assoc of FL

    4344 Central Ave33711St. PetersburgUnited States
  • Retina Vitreous Center

    1851 S Kelly Ave73013EdmondUnited States
  • Retina-Vitreous Associates Medical Group

    9001 Wilshire Blvd90211Beverly HillsUnited States
  • Retinal & Ophthalmic Cons PC

    1500 Tilton Rd08225NorthfieldUnited States
  • Retinal Consultants Med Group

    5775 Greenback Ln95841SacramentoUnited States
  • Retinal Diagnostic Center

    3395 S Bascom Ave95008CampbellUnited States
  • Retinal Research Institute, LLC

    85014PhoenixUnited States
  • Royal Free Hospital

    NW3 2QGLondonUnited Kingdom
  • Royal Liverpool University Hospital; St Paul's Clinical Eye Research Centre

    L7 8YELiverpoolUnited Kingdom
  • Royal Victoria Infirmary

    NE1 4LPNewcastle upon TyneUnited Kingdom
  • Samsung Medical Center

    06351SeoulSouth Korea
  • Selcuk University Faculty of Medicine; Department Of Ophthalmology

    KonyaTürkiye
  • Semmelweis Egyetem Szemészeti Vizsgálóhely

    39 Mária u.1085BudapestHungary
  • Seoul National University Bundang Hospital

    13620Seongnam-siSouth Korea
  • Seoul National University Hospital

    03080SeoulSouth Korea
  • Shiga University Of Medical Science Hospital

    520-2192OtsuJapan
  • Sierra Eye Associates

    950 Ryland St89502RenoUnited States
  • Singapore Eye Research Institute

    20 College Rd169856SingaporeSingapore
  • Sjællands Universitetshospital, Roskilde; Øjenafdelingen

    23 Vestermarksvej4000RoskildeDenmark
  • Southeast Retina Center

    3685 Wheeler Rd30909AugustaUnited States
  • Southeastern Retina Associates Chattanooga

    1606 Gunbarrel Rd37421ChattanoogaUnited States
  • Southern CA Desert Retina Cons

    36949 Cook St92211Palm DesertUnited States
  • Southern California Permanente Medical Group

    1515 N Vermont Ave90027Los AngelesUnited States
  • Southern Vitreoretinal Assoc

    2439 Care Dr32308TallahasseeUnited States
  • SP ZOZ Szpital Uniwersytecki w Krakowie Oddzia? Kliniczny Okulistyki i Onkologii Okulistycznej

    38 Mikołaja Kopernika31-501KrakówPoland
  • Spec. Ophth. Hospital for Active Treatment- Academic Pashev

    51 ul. "Emanuil Vaskidovich"1517SofiaBulgaria
  • Specialized Hospital for Active Treatment of Eye Diseases Zora

    20 bul. „Andrej Sakharov“1000SofiaBulgaria
  • Specjalistyczny O?rodek Okulistyczny Oculomedica

    14 Górzyskowo85-157BydgoszczPoland
  • SPEKTRUM Osrodek Okulistyki Klinicznej

    4 Zaolziańska53-334WrocławPoland
  • St James University Hospital

    LS9 7TFLeedsUnited Kingdom
  • St. Michael's Hospital; Department of Ophthalmology

    61 Queen St EM5C 2T2TorontoCanada
  • Strategic Clinical Research Group, LLC

    Willow ParkUnited States
  • Strathfield Retina Clinic

    9-13 Redmyre Rd2135StrathfieldAustralia
  • Sugita Eye Hospital

    460-0008NagoyaJapan
  • Sunderland Eye Infirmary

    SR2 9HPSunderlandUnited Kingdom
  • Sydney Eye Hospital

    8 Macquarie St2000SydneyAustralia
  • Sydney Retina Clinic and Day Surgery

    187 Macquarie St2000SydneyAustralia
  • Sydney West Retina

    2145WestmeadAustralia
  • Szegedi Tudományegyetem ÁOK; Department of Ophtalmology

    10-11 Korányi fasor6720SzegedHungary
  • Szpital Specjalistyczny nr 1; Oddzial Okulistyki

    7 Stefana Żeromskiego41-902BytomPoland
  • Szpital sw. Lukasza

    94B Bystrzańska43-309Bielsko-BiałaPoland
  • Taipei Veterans General Hospital; Ophthalmology

    201號 Section 2, Shipai Rd112Taipei CityTaiwan
  • Tan Tock Seng Hospital; Ophthalmology Department

    11 Jln Tan Tock Seng308433SingaporeSingapore
  • Tel Aviv Sourasky MC; Ophtalmology

    6 Weizmann StTel Aviv-YafoIsrael
  • Tennessee Retina PC

    345 23rd Ave N37203NashvilleUnited States
  • Texas Retina Associates

    10740 N Central Expy75231DallasUnited States
  • TG Laser Oftalmica

    666 Av. Dos de Mayo15073LimaPeru
  • The Lions Eye Institute

    6009NedlandsAustralia
  • The Ohio State University Havener Eye Institute

    915 Olentangy River Rd43212ColumbusUnited States
  • The Retina Care Center

    6115 Falls Rd21209BaltimoreUnited States
  • The Retina Consultants

    1220 New Scotland Rd12159SlingerlandsUnited States
  • The Retina Partners

    16500 Ventura Blvd91436Los AngelesUnited States
  • Toho University Sakura Medical Center

    285-0841SakuraJapan
  • Tokyo Medical University Hachioji Medical Center

    193-0998HachiojiJapan
  • Tokyo Women's Medical University

    162-8666Shinjuku CityJapan
  • Toronto Retina Institute

    6 Maginn MewsM3C 0G6TorontoCanada
  • Tufts Medical Center; Ophthalmology

    02116BostonUnited States
  • Uni of Vermont Medical Center;

    05405BurlingtonUnited States
  • Univ of Virginia Ophthalmology

    248 McCormick Rd22904CharlottesvilleUnited States
  • Universidade Federal de Sao Paulo - UNIFESP*X; Oftalmologia

    862 R. Botucatu04023-062São PauloBrazil
  • UNIVERSITA' DEGLI STUDI DI GENOVA - Di.N.O.G.;CLINICA OCULISTICA

    16132ArizonaItaly
  • Universitätsklinikum Carl Gustav Carus, Klinik und Poliklinik für Augenheilkunde

    74 Fetscherstraße01307DresdenGermany
  • Universitätsklinikum des Saarlandes; Klinik für Augenheilkunde

    22 Gebäude66421HomburgGermany
  • Universitätsklinikum Freiburg, Klinik für Augenheilkunde

    5 Killianstraße79106Freiburg im BreisgauGermany
  • Universitätsklinikum Magdeburg A.ö.R., Universitätsaugenklinik

    44 Leipziger Str.39120MagdeburgGermany
  • Universitätsklinikum Münster; Augenheilkunde

    15 Domagkstraße48149MünsterGermany
  • Universitätsklinikum Würzburg, Augenklinik und Poliklinik

    97080WürzburgGermany
  • University Health Network Toronto Western Hospital

    399 Bathurst StM5T 2S8TorontoCanada
  • University Hospital Southampton NHS Foundation Trust; Southampton Eye Unit

    103 Tremona RdSO16 6HUSouthamptonUnited Kingdom
  • University of Colorado; dept of ophthalmology

    1675 Aurora Ct80045AuroraUnited States
  • University of Miyazaki Hospital

    889-1601MiyazakiJapan
  • University of New Mexico

    87131AlbuquerqueUnited States
  • University of Utah; Division of Gastroenterology/Hepatology

    84132Salt Lake CityUnited States
  • University of Wisconsin

    MadisonUnited States
  • University Retina and Macula Associates, PC

    6320 W 159th St60452Oak ForestUnited States
  • Valley Retina Institute P.A.

    78550HarlingenUnited States
  • VISSUM Instituto Oftalmológico de Alicante

    1 C. del Cabañal03016alicante--alacant-Spain
  • Vista Klinik Ophthalmologische Klinik

    4102BinningenSwitzerland
  • Vitreo-Retinal Associates

    2505 E Paris Ave SE49546Grand RapidsUnited States
  • Vitreo-Retinal Associates, PC

    67 Belmont St01605WorcesterUnited States
  • Vitreo-Retinal Consultants

    530 N Lorraine Ave67214WichitaUnited States
  • VitreoRetinal Surgery, PLLC.; DBA Retina Consultants of Minnesota

    3601 W 76th St55435EdinaUnited States
  • Wagner Kapoor Institute

    6160 Kempsville Cir23502NorfolkUnited States
  • Wake Forest Baptist Health Eye Centre

    1 Medical Center Blvd27157Winston-SalemUnited States
  • West Coast Retina Medical Group

    1445 Bush St94109San FranciscoUnited States
  • West Virginia University Eye Institute

    1 Medical Center Dr26506MorgantownUnited States
  • Western Carolina Retinal Associate PA

    PennsylvaniaUnited States
  • Wolfe Eye Clinic

    50266West Des MoinesUnited States
  • Zala Megyei Kórház; SZEMESZET

    1 Zrínyi Miklós u.8900ZalaegerszegHungary
    Show study locations

    The source of the below information is public registry websites such as ClinicalTrials.gov, EuClinicalTrials.eu, ISRCTN.com, etc.. It has been summarised and edited into simpler language. For more information about this clinical study see the For Expert tab on the specific ForPatients page or follow these links to https://clinicaltrials.gov and/or https://euclinicaltrials.eu and/or https://www.isrctn.com.

    The below information is taken directly from public registry websites such as ClinicalTrials.gov, EuClinicalTrials.eu, ISRCTN.com, etc., and has not been edited.

    Results Disclaimer

    Study Summary

    This is a multicenter long-term extension study designed to evaluate the long-term safety and tolerability of faricimab administered by intravitreal (IVT) injection at a personalized treatment interval (PTI) to participants who enrolled in and completed one of the two Phase III studies, GR40349 (NCT03622580) or GR40398 (NCT03622593), also referred to as the parent studies.

    Hoffmann-La Roche Sponsor
    Phase 3 Phase
    NCT04432831, GR41987, 2020-000402-29 Study Identifier
    All Gender
    ≥18 Years Age
    No Healthy Volunteers

    How does the RHONE-X clinical trial work?
    This clinical trial is recruiting people who have a type of disease called diabetic macular edema. In order to take part, patients must have taken part in and completed either study GR40349 (also called ‘YOSEMITE’) or study GR40398 (also called ‘RHINE’). The purpose of this clinical trial is to test the long-term safety of faricimab for patients who have finished either of these two clinical trials.

    How do I take part in this clinical trial?
    To be able to take part in this clinical trial, you must have been diagnosed with diabetic macular edema and completed either study GR40349 (YOSEMITE’) or study GR40398 (‘RHINE’). If you are pregnant or breast feeding, you will not be able to take part.

    If you think this clinical trial may be suitable for you and would like to take part, please talk to your clinical trial doctor. They will give you all the information you need to make your decision about taking part in the clinical trial.

    You will have some further tests to make sure you will be able to take the treatments given in this clinical trial. Some of these tests or procedures may be part of your regular medical care. They may be done even if you do not take part in the clinical trial. If you have had some of the tests recently, they may not need to be done again.

    Before starting the clinical trial, you will be told about any risks and benefits of taking part in the trial. You will also be told what other treatments are available so that you may decide if you still want to take part.

    While taking part in the clinical trial, women (who are not currently pregnant but can become pregnant) will need to either not have heterosexual intercourse or take contraceptive medication for safety reasons.

    What treatment will I be given if I join this clinical trial?
    Everyone in this study will receive faricimab, given as an injection into the eye.

    During the first 4 months of this trial, everyone will come for a monthly visit to receive either a faricimab injection or a sham procedure. A sham procedure uses the blunt end of an empty syringe (without a needle) and presses it against the anesthetized eye to simulate a real injection. The sham procedures are to help people transition from their previous treatment on the YOSEMITE or RHINE trials.

    This first 4-month period of this trial is ‘masked’. This means that you will not know whether you are receiving faricimab or sham. After the first 4 months, the trial is ‘open label’. This means you will receive faricimab at a personalised treatment interval, where the number of visits and how frequently you receive injections will be calculated by the clinical trial doctor.

    How often will I be seen in follow-up appointments and for how long?
    You will be given faricimab at a personalised treatment interval for as long as it can help you. You are free to stop this treatment at any time. After being given treatment, you may still be contacted by the clinical trial doctors to check for any side effects you may be having.

     
     

    What happens if I am unable to take part in this clinical trial?
    If this clinical trial is not suitable for you, you will not be able to take part. Your doctor will suggest other clinical trials that you may be able to take part in or other treatments that you can be given. You will not lose access to any of your regular care.

    For more information about this clinical trial see the For Expert tab on the specific ForPatient page or follow this link to ClinicalTrials.gov: https://clinicaltrials.gov/ct2/show/NCT04432831
    Trial-identifier: NCT04432831
     

     

    Study Summary

    This is a multicenter long-term extension study designed to evaluate the long-term safety and tolerability of faricimab administered by intravitreal (IVT) injection at a personalized treatment interval (PTI) to participants who enrolled in and completed one of the two Phase III studies, GR40349 (NCT03622580) or GR40398 (NCT03622593), also referred to as the parent studies.

    Hoffmann-La Roche Sponsor
    Phase 3 Phase
    NCT04432831, GR41987, 2020-000402-29 Trial Identifier
    Faricimab, Sham Procedure Treatments
    Diabetic Macular Edema Condition
    Official Title

    A Multicenter, Open-Label Extension Study to Evaluate the Long-Term Safety and Tolerability of Faricimab in Patients With Diabetic Macular Edema

    Eligibility Criteria

    All Gender
    ≥18 Years Age
    No Healthy Volunteers
    Inclusion Criteria
    • Previous enrollment in and completion of Study GR40349 (NCT03622580) or GR40398 (NCT03622593), without study or study drug discontinuation
    • Ability to comply with the study protocol, in the investigator's judgment
    • For women of childbearing potential: agreement to remain abstinent or use acceptable contraceptive methods that result in a failure rate of <1% per year during the treatment period and for at least 3 months after the final dose of study treatment
    Exclusion Criteria
    • Pregnant or breastfeeding, or intending to become pregnant during the study or within 3 months after the final intravitreal injection of faricimab
    • Presence of other ocular diseases that give reasonable suspicion of a disease or condition that contraindicates the use of faricimab, that might affect interpretation of the results of the study or that renders the patient at high risk for treatment complications
    • Presence of other diseases, metabolic dysfunction, or clinical laboratory finding giving reasonable suspicion of a disease or condition that contraindicates the use of faricimab and that might affect interpretation of the results of the study or that renders the patient at high risk of treatment complications
    • History of a severe allergic reaction or anaphylactic reaction to a biologic agent or known hypersensitivity to any component of the faricimab injections, study treatment procedure, dilating drops, or any of the anesthetic and antimicrobial preparations used by a patient during the study
    • Requirement for continuous use of any medications or treatments indicated as prohibited therapy

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