BN40697 - A study to look at tominersen safety over 15 months in people with Huntington’s disease

An Open-Label Extension Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7234292 (ISIS 443139) in Huntington's Disease Patients Who Participated in Prior Investigational Studies of RO7234292 (ISIS 443139)

Neurodegenerative Disorder
Huntington Disease (HD)

For Medical Professional
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Basic Details

Sponsor Hoffmann-La Roche

Phase Phase 2

Trial Identifier NCT03342053, BN40697, ISIS 443139-CS2

Condition Huntington's Disease

Official Title An Open-Label Extension Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7234292 (ISIS 443139) in Huntington's Disease Patients Who Participated in Prior Investigational Studies of RO7234292 (ISIS 443139)

Study Summary

This study will test the safety, tolerability, pharmacokinetics and pharmacodynamics of RO7234292 administered intrathecally to adult patients with Huntington's Disease.

Eligibility Criteria

Gender

All

Age

≥25 Years

Healthy Volunteers

Inclusion Criteria

Must have completed dosing in ISIS 443139-CS1

Exclusion Criteria

Any new condition or worsening of existing condition that could make the patient unsuitable for participation or interfere with the patient participating in and/or completing the study

The source of the below information is public registry websites such as ClinicalTrials.gov, EuClinicalTrials.eu, ISRCTN.com, etc.. It has been summarised and edited into simpler language. For more information about this clinical study see the For Expert tab on the specific ForPatients page or follow these links to https://clinicaltrials.gov and/or https://euclinicaltrials.eu and/or https://www.isrctn.com.

The information is taken directly from public registry websites such as ClinicalTrials.gov, EuClinicalTrials.eu, ISRCTN.com, etc., and has not been edited.

Results Disclaimer

What is Clinical Research?

In clinical research, volunteers, researchers, and medical professionals work together toward a shared goal: better treatment outcomes for patients. Clinical trials are vital to their process. They are carefully designed and follow approved protocols.

BN40697 - A study to look at tominersen safety over 15 months in people with Huntington’s disease

Basic Details

Study Summary

Eligibility Criteria

What is Clinical Research?

For the latest version of this information please go to www.forpatients.roche.com

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BN40697 - A study to look at tominersen safety over 15 months in people with Huntington’s disease

For the latest version of this information please go to www.forpatients.roche.com